6-Thien-2-ylnicotinaldehyde

Base Information

• Chemical Name: 6-Thien-2-ylnicotinaldehyde
• CAS No.: 834884-61-6
• Molecular Formula: C₁₀H₇NOS
• Molecular Weight: 189.238
• Hs Code.: 2934999090
• Mol file: 834884-61-6.mol

Synonyms:6-(2-Thienyl)pyridine-3-carbaldehyde;

Chemical Property of 6-Thien-2-ylnicotinaldehyde

Chemical Property:

• Vapor Pressure: 8.88E-05mmHg at 25°C
• Melting Point: 95 °C
• Refractive Index: 1.645
• Boiling Point: 340 °C at 760 mmHg
• Flash Point: 159.4 °C
• PSA: 58.20000
• Density: 1.269 g/cm³
• LogP: 2.62260

Purity/Quality:

98%min ^*data from raw suppliers

6-thien-2-ylnicotinaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-Thien-2-ylnicotinaldehyde

There total 1 articles about 6-Thien-2-ylnicotinaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

thiophene boronic acid (6165-68-0) + 6-bromonicotinaldehyde (149806-06-4) → 5-formyl-2-pyridylthiophene (834884-61-6)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; potassium carbonate; In 1,2-dimethoxyethane; water; at 80 ℃; for 14h;

DOI:10.1002/adsc.202000825

upstream raw materials:

thiophene boronic acid

6-bromonicotinaldehyde

Refernces