(1-Methyl-1H-pyrrol-2-yl)methanamine

Base Information

• Chemical Name: (1-Methyl-1H-pyrrol-2-yl)methanamine
• CAS No.: 69807-81-4
• Molecular Formula: C6H10 N2
• Molecular Weight: 110.159
• Hs Code.: 2933990090
• European Community (EC) Number: 817-750-7
• DSSTox Substance ID: DTXSID00379889
• Nikkaji Number: J934.872G
• Wikidata: Q27452764
• Mol file: 69807-81-4.mol

Synonyms:69807-81-4;(1-Methyl-1H-pyrrol-2-yl)methanamine;(1-Methyl-1H-Pyrrol-2-Yl)Methylamine;(1-methylpyrrol-2-yl)methanamine;1-(1-methyl-1H-pyrrol-2-yl)methanamine;1-methyl-1h-pyrrole-2-methanamine;1H-Pyrrole-2-methanamine, 1-methyl-;SCHEMBL246455;2-(Aminomethyl)-1-methylpyrrole;DTXSID00379889;GGCBARJYVAPZJQ-UHFFFAOYSA-N;1H-Pyrrole-2-methanamine,1-methyl-;BBL029743;MFCD02677708;STK893144;AKOS002671722;CS-W005958;PS-4252;SB63918;(1-methyl-1H-pyrrol-2-yl)rnethylarnine;C-(1-methyl-1H-pyrrol-2-yl)methylamine;C-(1-Methyl-1H-pyrrol-2-yl)-methylamine;BB 0262289;FT-0604519;EN300-95909;A866743;J-500230;Q27452764;F2169-1279;Z362827744

Chemical Property of (1-Methyl-1H-pyrrol-2-yl)methanamine

Chemical Property:

• Vapor Pressure: 0.338mmHg at 25°C
• Boiling Point: 58 °C
• Flash Point: 74.5°C
• PSA: 30.95000
• Density: 1.03g/cm³
• LogP: 1.18410
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• XLogP3: -0.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 110.084398327
• Heavy Atom Count: 8
• Complexity: 72.9

Purity/Quality:

98%,99%, ^*data from raw suppliers

(1-Methyl-1H-pyrrol-2-yl)methylamine ^*data from reagent suppliers

Safty Information:

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN1C=CC=C1CN

Technology Process of (1-Methyl-1H-pyrrol-2-yl)methanamine

There total 10 articles about (1-Methyl-1H-pyrrol-2-yl)methanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-methyl-1H-pyrrole-2-carbaldehyde oxime (55970-42-8) → 2-aminomethyl-1-methyl-1H-pyrrole (69807-81-4)

Guidance literature:

With hydrogen; In ethanol; at 20 ℃; under 3040.2 Torr;

DOI:10.1016/j.ejmech.2016.02.015

Reference yield:

(1-methyl-1H-pyrrole-2-yl)-methanol (52160-51-7) → 2-aminomethyl-1-methyl-1H-pyrrole (69807-81-4)

Guidance literature:

With aq.ammonium hydroxide; nickel; at 20 ℃; under 2585.81 Torr;

DOI:10.1021/jm015545y

Reference yield:

N-methylpyrrole aldehyde (1192-58-1) → 2-aminomethyl-1-methyl-1H-pyrrole (69807-81-4)

Guidance literature:

With ammonium hydroxide; hydrogen; nickel;

DOI:10.1021/jm0210818

upstream raw materials:

1-methylpyrrol-2-carboxaldoxime

1-methyl-1H-pyrrole-2-carboxamide

1-methyl-1H-pyrrole-2-carbonitrile

N-methylpyrrole aldehyde

Downstream raw materials:

1-methyl-2-aminomethyl-pyrrolidine

JAC₀₁₁₇₉-6

1-(1-methyl-1H-pyrrol-2-ylmethyl)-3-phenethylthiourea

C₁₈H₁₇F₃N₄O₂S

Refernces

• 1、 López-Rodríguez, María L.,Viso, Alma,Ortega-Gutiérrez, Silvia,Fowler, Christopher J.,Tiger, Gunnar,De Lago, Eva,Fernández-Ruiz, Javier,Ramos, José A.. "Design, synthesis, and biological evaluation of new inhibitors of the endocannabinoid uptake: Comparison with effects on fatty acid amidohydrolase". . p. 1512 - 1522. Retrieved 2007/10/03.
• 2、 Brueckner, Christian,Xie, Lily Y.,Dolphin, David. "The reductive coupling of 2-cyanopyrroles: A study pertaining to the mechanism of formation of porphocyanines". . p. 2021 - 2030. Retrieved 2007/10/03.