C₁₀H₉Br₂Cl

Base Information

• Chemical Name: C₁₀H₉Br₂Cl
• CAS No.: 1064000-91-4
• Molecular Formula: C₁₀H₉Br₂Cl
• Molecular Weight: 324.442
• Mol file: 1064000-91-4.mol

Synonyms:C₁₀H₉Br₂Cl

Chemical Property of C₁₀H₉Br₂Cl

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₀H₉Br₂Cl

There total 2 articles about C₁₀H₉Br₂Cl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Bromoform (75-25-2) + 1-chloro-2-(prop-1-en-2-yl)benzene (3609-45-8) → C10H9Br2Cl (1064000-91-4)

Guidance literature:

With sodium hydroxide; cetyltrimethylammonim bromide; In dichloromethane; water; at 20 ℃; for 48h;

DOI:10.1016/j.tet.2008.06.087

Reference yield:

1-(2-chlorophenyl)ethanone (2142-68-9) → C10H9Br2Cl (1064000-91-4)

Guidance literature:

Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran / 22 h / 0 - 25 °C / Inert atmosphere

1.2: 48 h / 0 - 25 °C / Inert atmosphere

2.1: sodium hydroxide / dichloromethane / 24 h / 25 °C / Inert atmosphere

With n-butyllithium; sodium hydroxide; In tetrahydrofuran; dichloromethane;

DOI:10.1021/acs.orglett.0c02071

Reference yield:

C10H9Br2Cl (1064000-91-4) → 1-(buta-2,3-dien-2-yl)-2-chlorobenzene

Guidance literature:

With ethylmagnesium bromide; In tetrahydrofuran; diethyl ether; at 20 ℃; for 1h; Inert atmosphere;

DOI:10.1055/s-0039-1690207

upstream raw materials:

Bromoform

1-chloro-2-(prop-1-en-2-yl)benzene

1-(2-chlorophenyl)ethanone

Downstream raw materials:

2,3-diethoxybutane

Refernces

• 1、 Gates, Ashley M.,Santos, Webster L.. "Regioselective Diboron-Mediated Semireduction of Terminal Allenes". supporting information. p. 4619 - 4624. Retrieved 2019/12/11.