trans-1-Iodo-1-octen-3-one

Base Information

• Chemical Name: trans-1-Iodo-1-octen-3-one
• CAS No.: 39178-64-8
• Molecular Formula: C8H13 I O
• Molecular Weight: 252.095
• Hs Code.: 2914700090
• Mol file: 39178-64-8.mol

Synonyms:1-Octen-3-one,1-iodo-, (E)-; (E)-1-Iodo-1-octen-3-one; trans-1-Iodo-1-octen-3-one

Chemical Property of trans-1-Iodo-1-octen-3-one

Chemical Property:

• Vapor Pressure: 0.016mmHg at 25°C
• Melting Point: 37.7-38.4oC
• Boiling Point: 256oC
• Flash Point: 108 ºC
• PSA: 17.07000
• Density: 1.481
• LogP: 3.08450

Purity/Quality:

98%Min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trans-1-Iodo-1-octen-3-one

There total 3 articles about trans-1-Iodo-1-octen-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

oct-1-yn-3-one (27593-19-7) → (E)-1-iodo-1-octen-3-one (39178-64-8)

Guidance literature:

With sodium iodide; In trifluoroacetic acid; for 0.5h; Ambient temperature;

DOI:10.1016/S0040-4039(00)85059-5

Reference yield: 38.0%

oct-1-yn-3-one (27593-19-7) + benzaldehyde (100-52-7) → (E)-1-iodo-1-octen-3-one (39178-64-8) + (E)-2-(Hydroxy-phenyl-methyl)-1-iodo-oct-1-en-3-one (109572-55-6) + (Z)-2-(Hydroxy-phenyl-methyl)-1-iodo-oct-1-en-3-one (109572-44-3)

Guidance literature:

With trimethylsilyl iodide; titanium tetrachloride; In dichloromethane; at -78 ℃;

DOI:10.1016/S0040-4039(00)85060-1

Reference yield: 17.0%

oct-1-yn-3-one (27593-19-7) → (E)-1-iodo-1-octen-3-one (39178-64-8) + cis-1-iodo-1-octen-3-one (108161-46-2)

Guidance literature:

With sodium iodide; In acetic acid; for 0.5h; Product distribution; Ambient temperature; various acetylenic ketones, iodinating reagents, solvents and reaction conditions;

DOI:10.1016/S0040-4039(00)85059-5

upstream raw materials:

oct-1-yn-3-one

benzaldehyde

Downstream raw materials:

(S)-(E)-(+)-1-Iodo-1-octen-3-ol

(R)-(E)-1-Iodo-1-octene-3-ol

(E)-1-phenyloct-1-en-3-one

(R)-1-((2R,3R)-3-Iodo-oxiranyl)-hexan-1-ol

Refernces

• 1、 Fujisawa, Tamotsu,Tanaka, Akihito,Ukaji, Yutaka. "Stereoselective Conjugate Addition of Halide Anion to Acetylenic Carbonyl Compounds Promoted by Lanthanoid Reagents". . p. 1255 - 1256. Retrieved 2007/10/02.
• 2、 Taniguchi, Mikio,Hino, Tohru,Kishi, Yoshito. "ALDOL REACTION OF ALLENOLATES GENERATED VIA 1,4-ADDITION OF IODIDE ANION OR ITS EQUIVALENT TO α,β-ACETYLENIC KETONES". . p. 4767 - 4770. Retrieved 2007/10/02.