2-bromo-3-nitro-phenetole

Base Information

• Chemical Name: 2-bromo-3-nitro-phenetole
• CAS No.: 908355-78-2
• Molecular Formula: C₈H₈BrNO₃
• Molecular Weight: 246.06
• Mol file: 908355-78-2.mol

Synonyms:2-bromo-3-nitro-phenetole

Chemical Property of 2-bromo-3-nitro-phenetole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 2-bromo-3-nitro-phenetole

There total 2 articles about 2-bromo-3-nitro-phenetole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Amino-3-nitrophenol (603-85-0) → 2-bromo-3-nitro-phenetole (908355-78-2)

Guidance literature:

Multi-step reaction with 2 steps

1: K₂CO₃ / dimethylformamide / 20 °C

2: NaNO₂; aq. H₂SO₄; CuBr / aq. HBr

With sulfuric acid; potassium carbonate; copper(I) bromide; sodium nitrite; hydrogen bromide; In N,N-dimethyl-formamide; 2: Sandmeyer reaction;

DOI:10.1021/jm051146h

Reference yield:

2-amino-3-ethoxynitrobenzene (6036-46-0) → 2-bromo-3-nitro-phenetole (908355-78-2)

Guidance literature:

With sulfuric acid; copper(I) bromide; sodium nitrite; hydrogen bromide;

DOI:10.1021/jm051146h

Reference yield:

2-bromo-3-nitro-phenetole (908355-78-2) → 3-ethoxy-2-bromo-aniline (908355-80-6)

Guidance literature:

With hydrogenchloride; tin;

upstream raw materials:

2-amino-3-ethoxynitrobenzene

2-Amino-3-nitrophenol

Downstream raw materials:

3-ethoxy-2-bromo-aniline

7-ethoxy-benzothiazole-2-thiol

Refernces