603-85-0 Usage
Description
2-Amino-3-nitrophenol is an organic compound with the chemical formula C6H6N2O3. It is characterized by the presence of an amino group (-NH2) at the 2nd position and a nitro group (-NO2) at the 3rd position on a phenol ring. 2-Amino-3-nitrophenol is known for its versatile applications in various industries.
Uses
Used in Cosmetic Industry:
2-Amino-3-nitrophenol is used as a semipermanent (nonoxidative) hair colorant and as a toner in permanent (oxidative) hair dye products. It provides a wide range of color options and enhances the overall appearance of hair.
Used in Mass Spectrometry:
2-Amino-3-nitrophenol is used as a matrix during visible matrix-assisted laser desorption/ionization (VIS-MALDI) mass spectrometry. It helps in the ionization of large biomolecules, enabling their analysis and identification.
Used in Chemical Synthesis:
2-Amino-3-nitrophenol is used in the preparation of 1,3-benzoxazole-4,7-dione, a heterocyclic compound with potential applications in pharmaceuticals and materials science. Its synthesis involves the cyclization of 2-amino-3-nitrophenol with appropriate reagents, resulting in the formation of the desired benzoxazole derivative.
Check Digit Verification of cas no
The CAS Registry Mumber 603-85-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,0 and 3 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 603-85:
(5*6)+(4*0)+(3*3)+(2*8)+(1*5)=60
60 % 10 = 0
So 603-85-0 is a valid CAS Registry Number.
InChI:InChI=1/C6H6N2O3/c7-6-4(8(10)11)2-1-3-5(6)9/h1-3,9H,7H2
603-85-0Relevant articles and documents
SYNTHESIS OF 4-HYDROXY-1-METHYLBENZIMIDAZOLE AND 7-HYDROXY-1-METHYLBENZIMIDAZOLE
Katritzky, Alan R.,Musgrave, Richard P.,Rachwal, Bogumila,Zaklika, Chris
, p. 345 - 352 (2007/10/03)
4-Hydroxy-1-methylbenzimidazole (1) was synthesized via condensation of 2-amino-3-nitrophenol (3) with trimethyl orthoformate, reduction of the resulting 4-nitrobenzoxazole (4) to amine (5), reaction with hydroxymethylbenzotriazole to form benzotriazolyl adduct (6), reduction to give 4-methylaminobenzoxazole (7), and finally base catalyzed rearrangement.The synthesis of 7-hydroxy-1-methylbenzimidazole (2) was accomplished by reduction of 4 with sodium borohydride to form 3-nitro-2-methylaminophenol (8), followed by hydrogenation to give amino derivative (9) and condensation with trimethyl orthoformate.