603-84-9

Basic information

• Product Name: 2-chloro-3-nitro-phenol
• Synonyms: 2-chloro-3-nitro-phenol;Phenol, 2-chloro-3-nitro-;2-Chlor-3-nitro-1-hydroxy-benzol;3-hydroxy-2-chloronitrobenzene;2-Chlor-3-nitrophenol
• CAS NO: 603-84-9
• Molecular Formula: C₆H₄ClNO₃
• Molecular Weight: 173.55
• Product Categories: API intermediates;Chlorine Compounds;Nitro Compounds
• Mol File: 603-84-9.mol
• Article Data: 11

Chemical Properties

• Melting Point: 120.5 °C
• Boiling Point: 279.6 °C at 760 mmHg
• Flash Point: 122.9 °C
• Appearance: Orange crystalline powder
• Density: 1.554 g/cm³
• Vapor Pressure: 0.002mmHg at 25°C
• Refractive Index: 1.627
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 7.39±0.25(Predicted)
• CAS DataBase Reference: 2-chloro-3-nitro-phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-3-nitro-phenol(603-84-9)
• EPA Substance Registry System: 2-chloro-3-nitro-phenol(603-84-9)

Safety Data

• Hazardous Substances Data: 603-84-9(Hazardous Substances Data)

Usage

General Description

2-chloro-3-nitro-phenol is a chemical compound with the molecular formula C6H4ClNO3. It is a pale yellow solid that is commonly used as an intermediate in the production of pharmaceuticals, dyes, and pesticides. 2-chloro-3-nitro-phenol is classified as a chlorinated nitrophenol, and is known to be toxic and harmful if ingested, inhaled or absorbed through the skin. 2-chloro-3-nitro-phenol is also considered to be harmful to the environment, as it can be hazardous to aquatic organisms and may persist in the environment for a long time. Therefore, proper handling and disposal of this chemical compound is essential to minimize its potential impact on human health and the environment.

InChI:InChI=1/C6H4ClNO3/c7-6-4(8(10)11)2-1-3-5(6)9/h1-3,9H

Upstream product

• 16315-07-4 2,3-dinitroanisole 
• 121-88-0 5-Nitro-2-aminophenol 
• 603-85-0 2-Amino-3-nitrophenol 
• 99-09-2 3-nitro-aniline 
• 885-81-4 N-(4-ethoxy-2-nitrophenyl)acetamide 
• 16554-45-3 2-methoxy-6-nitroaniline 
• 62-44-2 4-ethoxyacetanilide 
• 554-84-7 meta-nitrophenol 
• 7782-50-5 chlorine 
• 846031-57-0 2-chloro-3-nitro-phenetole 
• 3970-39-6 2-chloro-3-methoxynitrobenzene 
• 62153-30-4 acetic acid-(4-methoxy-2,3-dinitro-anilide) 
• 861086-17-1 acetic acid-(4-ethoxy-3-chloro-2-nitro-anilide) 
• 5473-00-7 4-methoxy-2,3-dinitro-aniline 

Downstream Products

• 1336964-16-9 2-chloro-3-[(1-methylethyl)oxy]aniline 
• 80117-38-0 2-chloro-1-nitro-3-phenylmethoxybenzene 
• 163120-56-7 1-(2-chloro-3-nitrophenoxy)propan-2-amine 
• 16762-88-2 4-Chlor-2-brom-2'-nitro-6'-isopropyloxy-diphenylsulfid 
• 3926-65-6 2-Chlor-6-hydroxy-10-(3-dimethylamino-propyl)-phenthiazin 
• 122484-85-9 1-(2-ethoxyethyl)-2-(hexahydro-4-methyl-5-oxo-1H-1,4-diazepin-1-yl)-6-phenylmethoxy-1H-benzimidazole 
• 122484-84-8 1-(2-ethoxyethyl)-2-(hexahydro-5-oxo-1H-1,4-diazepin-1-yl)-6-phenylmethoxy-1H-benzimidazole 
• 122484-82-6 1-(2-ethoxyethyl)-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-7-phenylmethoxy-1H-benzimidazole 
• 122484-91-7 (2-Benzyloxy-6-nitro-phenyl)-(2-ethoxy-ethyl)-amine 
• 122484-80-4 2-chloro-1-(2-ethoxyethyl)-7-phenylmethoxy-1H-benzimidazole 

Relevant articles and documents

TRPV4 ANTAGONISTS

The present invention relates to quinoline analogs, pharmaceutical compositions containing them and their use as TRPV4 antagonists.

Hepatitis C inhibitor peptide analogs

Compounds of formula (I): wherein R1, R2, R3, R4, R5, Y, n and m are as defined herein. The compounds are useful as inhibitors of HCV NS3 protease.

HEPATITIS C INHIBITOR PEPTIDE ANALOGS

The invention relates to compounds of formula (I) wherein R', R2, R3, R4, R5, R6, Y, n and m are as defined herein. The compounds are useful for the treatment and prevention of hepatitis C viral infections in mammals by inhibiting HCV NS3 protease. The invention further relates to azalactone compounds of the formula (III) which can be reacted with an amide anion to produce the compounds of formula (I).