1-Trimethylsilyl-5-fluoro-1,4-dihydronaphthalen-1,4-endoxide

Base Information

• Chemical Name: 1-Trimethylsilyl-5-fluoro-1,4-dihydronaphthalen-1,4-endoxide
• CAS No.: 134965-27-8
• Molecular Formula: C₁₃H₁₅FOSi
• Molecular Weight: 234.345
• Mol file: 134965-27-8.mol

Synonyms:1-Trimethylsilyl-5-fluoro-1,4-dihydronaphthalen-1,4-endoxide

Chemical Property of 1-Trimethylsilyl-5-fluoro-1,4-dihydronaphthalen-1,4-endoxide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 1-Trimethylsilyl-5-fluoro-1,4-dihydronaphthalen-1,4-endoxide

There total 1 articles about 1-Trimethylsilyl-5-fluoro-1,4-dihydronaphthalen-1,4-endoxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-furyltrimethylsilane (1578-33-2) + 1,3-Difluorobenzene (372-18-9) → 1-Trimethylsilyl-5-fluoro-1,4-dihydronaphthalen-1,4-endoxide (134965-27-8) + 1-Trimethylsilyl-8-fluoro-1,4-dihydronaphthalen-1,4-endoxide (134965-26-7)

Guidance literature:

With tert.-butyl lithium; Yield given. Multistep reaction; 1.) THF, pentane, -70 deg C, 15 min, 2a.) up to room temperature, 2 h, 2b.) room temperature, 11 h;

DOI:10.1002/mrc.1260290504

upstream raw materials:

2-furyltrimethylsilane

1,3-Difluorobenzene

Refernces

• 1、 Gribble, Gordon W.,Keavy, Daniel J.,Olson, Erik R.,Rae, Ian D.,Staffa, Alfred,et al.. "Fluorine Deshielding in the Proximity of a Methyl Group. An Experimental and Theoretical Study". . p. 422 - 432. Retrieved 2007/10/02.