2-TRIMETHYLSILYLFURAN

Base Information

• Chemical Name: 2-TRIMETHYLSILYLFURAN
• CAS No.: 1578-33-2
• Molecular Formula: C7H12OSi
• Molecular Weight: 140.257
• Hs Code.: 2932190090
• Mol file: 1578-33-2.mol

Synonyms:Silane,2-furanyltrimethyl- (9CI);Silane, 2-furyltrimethyl- (7CI,8CI);2-(Trimethylsilyl)furan;2-Furyltrimethylsilane;

Chemical Property of 2-TRIMETHYLSILYLFURAN

Chemical Property:

• Boiling Point: 134.9 °C at 760 mmHg
• Flash Point: 35.4 °C
• PSA: 13.14000
• Density: 0.89 g/cm³
• LogP: 1.82480

Purity/Quality:

98%Min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-TRIMETHYLSILYLFURAN

There total 14 articles about 2-TRIMETHYLSILYLFURAN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2,3-butadienoyltrimethylsilane → 2-furyltrimethylsilane (1578-33-2)

Guidance literature:

gas chromatography;

DOI:10.1080/00397919508011383

Reference yield: 89.0%

2,5-dibromofuran (32460-00-7) + chloro-trimethyl-silane (75-77-4) → 2-furyltrimethylsilane (1578-33-2) + 2,5-bis(trimethylsilyl)-furane (1578-29-6)

Guidance literature:

With tetrabutylammomium bromide; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; Yields of byproduct given; electrochemical conditions (Mg anode, 2.2 F_.mol^-1);

DOI:10.1016/S0022-328X(98)00853-5

Reference yield: 88.0%

2-bromofuran (584-12-3) + chloro-trimethyl-silane (75-77-4) → 2-furyltrimethylsilane (1578-33-2)

Guidance literature:

With tetrabutylammomium bromide; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; electrochemical conditions;

DOI:10.1016/S0022-328X(98)00853-5

upstream raw materials:

furan

n-butyllithium

chloro-trimethyl-silane

2-lithiofuran

Downstream raw materials:

2-acetyl-5-(trimethylsilyl)furan

5-(trimethylsilyl)furan-2-carboxylic acid

2,5-bis(trimethylsilyl)-furane

trimethylsilan

Refernces

• 1、 Raheem, Mohammed-Abdul,Tam, William. "Synthesis of C1-substituted 7-oxanorbornadienes". . p. 260 - 267,8. Retrieved 2013.
• 2、 Frogneux, Xavier,Von Wolff, Niklas,Thuéry, Pierre,Lefèvre, Guillaume,Cantat, Thibault. "CO2 Conversion into Esters by Fluoride-Mediated Carboxylation of Organosilanes and Halide Derivatives". supporting information. p. 2930 - 2934. Retrieved 2016/03/25.
• 3、 Huang, Bin,Guo, Lei,Jia, Yanxing. "Protecting-Group-Free Enantioselective Synthesis of (-)-Pallavicinin and (+)-Neopallavicinin". supporting information. p. 13599 - 13603. Retrieved 2015/11/16.