1-phenyl-3-benzylsalicyloyl-5,5-diethylbarbituric acid

Base Information

• Chemical Name: 1-phenyl-3-benzylsalicyloyl-5,5-diethylbarbituric acid
• CAS No.: 75579-31-6
• Molecular Formula: C₂₈H₂₆N₂O₅
• Molecular Weight: 470.525
• Mol file: 75579-31-6.mol

Synonyms:1-phenyl-3-benzylsalicyloyl-5,5-diethylbarbituric acid

Chemical Property of 1-phenyl-3-benzylsalicyloyl-5,5-diethylbarbituric acid

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 1-phenyl-3-benzylsalicyloyl-5,5-diethylbarbituric acid

There total 1 articles about 1-phenyl-3-benzylsalicyloyl-5,5-diethylbarbituric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.0%

2-benzyloxybenzoyl chloride (4349-62-6) + C14H15N2O3(1-)*Ag(1+) → 1-phenyl-3-benzylsalicyloyl-5,5-diethylbarbituric acid (75579-31-6)

Guidance literature:

In Petroleum ether; for 40h; Heating;

Reference yield: 82.0%

1-phenyl-3-benzylsalicyloyl-5,5-diethylbarbituric acid (75579-31-6) → 1-phenyl-3-salicyloyl-5,5-diethylbarbituric acid (75565-57-0)

Guidance literature:

With hydrogen; trimethyleneglycol; In tetrahydrofuran;

Reference yield:

1-phenyl-3-benzylsalicyloyl-5,5-diethylbarbituric acid (75579-31-6) → 1-phenyl-3-o-acetoxybenzoyl-5,5-diethylbarbituric acid

Guidance literature:

Multi-step reaction with 2 steps

1: 82 percent / hydrogen / PdO / tetrahydrofuran

2: 64 percent / 7 h

With hydrogen; trimethyleneglycol; In tetrahydrofuran;

upstream raw materials:

2-benzyloxybenzoyl chloride

Downstream raw materials:

1-phenyl-3-salicyloyl-5,5-diethylbarbituric acid

Refernces