methyl 2-hydroxy-4-isopropyl benzoate

Base Information

• Chemical Name: methyl 2-hydroxy-4-isopropyl benzoate
• CAS No.: 163618-93-7
• Molecular Formula: C₁₁H₁₄O₄
• Molecular Weight: 210.23
• Mol file: 163618-93-7.mol

Synonyms:methyl 2-hydroxy-4-isopropyl benzoate

Chemical Property of methyl 2-hydroxy-4-isopropyl benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2-hydroxy-4-isopropyl benzoate

There total 18 articles about methyl 2-hydroxy-4-isopropyl benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

methyl 2-benzyloxy-4-isopropyl benzoate (945745-53-9) → methyl 2-hydroxy-4-isopropyl benzoate (163618-93-7)

Guidance literature:

With methanol; silica-immobilized p-TsOH; In toluene; at 80 ℃; for 4h;

DOI:10.1016/j.tet.2009.03.089

Reference yield: 95.0%

methyl 4-isopropoxy-2-methoxymethyloxybenzoate (1165713-09-6) → methyl 2-hydroxy-4-isopropyl benzoate (163618-93-7)

Guidance literature:

With silica-immobilized p-TsOH; In toluene; at 20 ℃; for 0.5h;

DOI:10.1016/j.tet.2009.03.089

Reference yield: 90.0%

methyl 4-isopropoxy-2-methoxymethyloxybenzoate (1165713-09-6) → bis-(methyl-2-hydroxy-4-isopropoxybenzo-5-yl)methane (1165713-54-1) + methyl 2-hydroxy-4-isopropyl benzoate (163618-93-7)

Guidance literature:

With amberlyst-15; In toluene; at 20 ℃; for 0.83h;

DOI:10.1016/j.tet.2009.03.089

upstream raw materials:

methanol

2-hydroxy-4-isopropoxybenzoic acid

Ipriflavone

methyl 2,4-dihydroxybenzoate

Downstream raw materials:

methyl 2-benzyloxy-4-isopropyl benzoate

methyl 4-isopropoxy-2-methoxymethyloxybenzoate

methyl 4-isopropoxy-2-(4-methoxy-benzyloxy)benzoate

methyl 4-isopropoxy-2-methoxybenzoate

Refernces

• 1、 Ploypradith, Poonsakdi,Cheryklin, Pannarin,Niyomtham, Nattisa,Bertoni, Daniel R.,Ruchirawat, Somsak. "Solid-supported acids as mild and versatile reagents for the deprotection of aromatic ethers". . p. 2637 - 2640. Retrieved 2008/02/08.
• 2、 Varga, Marton,Batori, Sandor,Koevari-Radkai, Maria,Prohaszka-Nemet, Ildiko,Vitanyi-Morvai, Magdolna,Boecskey, Zsolt,Bokotey, Sandor,Simon, Kalman,Hermecz, Istvan. "Stability and chemical reactivity of 7-isopropoxyisoflavone (ipriflavone)". . p. 3911 - 3920. Retrieved 2007/10/03.