Technology Process of 2-amino-3-nitrobenzoyl chloride
There total 5 articles about 2-amino-3-nitrobenzoyl chloride which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 93 percent / Br2; aq. KOH / 3 h / 60 °C
2: SOCl2 / tetrahydrofuran; dimethylformamide / 20 °C
With
potassium hydroxide; thionyl chloride; bromine;
In
tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/jm000950v
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: ammonium hydroxide / 2.5 h / 0 - 15 °C / Inert atmosphere; Large scale
1.2: 20 °C / Inert atmosphere; Large scale
2.1: potassium hydroxide; bromine / water / 1.5 h / 0 - 75 °C / Inert atmosphere; Large scale
3.1: thionyl chloride / 1,2-dimethoxyethane / 12 h / 50 °C / Large scale
With
ammonium hydroxide; thionyl chloride; bromine; potassium hydroxide;
In
1,2-dimethoxyethane; water;
2.1: |Hofmann Rearrangement;
DOI:10.1021/op7000194
