(3-Phenoxyphenyl)hydrazine hydrochloride

Base Information

• Chemical Name: (3-Phenoxyphenyl)hydrazine hydrochloride
• CAS No.: 109221-90-1
• Molecular Formula: C12H12 N2 O . Cl H
• Molecular Weight: 236.701
• Hs Code.: 2928000090
• European Community (EC) Number: 808-849-6
• Mol file: 109221-90-1.mol

Synonyms:109221-90-1;(3-phenoxyphenyl)hydrazine hydrochloride;(3-PHENOXY-PHENYL)-HYDRAZINE HYDROCHLORIDE;(3-phenoxyphenyl)hydrazine;hydrochloride;(3-Phenoxyphenyl)hydrazine HCl;(3-Phenoxy-phenyl)-hydrazine HCl;SCHEMBL4376342;AB9886;MFCD06738786;(3-phenoxyphenyl)hydrazinehydrochloride;AKOS027327823;AB27889;AS-44997;EN300-7360691;A801981;(3-Phenoxy-phenyl)-hydrazine hydrochloride, AldrichCPR

Chemical Property of (3-Phenoxyphenyl)hydrazine hydrochloride

Chemical Property:

• Vapor Pressure: 1.83E-07mmHg at 25°C
• Boiling Point: 420.2°C at 760 mmHg
• Flash Point: 208°C
• PSA: 47.28000
• LogP: 4.12650
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 236.0716407
• Heavy Atom Count: 16
• Complexity: 181

Purity/Quality:

98%Min ^*data from raw suppliers

(3-Phenoxyphenyl)hydrazineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)OC2=CC=CC(=C2)NN.Cl

Technology Process of (3-Phenoxyphenyl)hydrazine hydrochloride

There total 1 articles about (3-Phenoxyphenyl)hydrazine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

3-phenoxyaniline (3586-12-7) → (3-phenoxyphenyl)hydrazine hydrochloride (109221-90-1)

Guidance literature:

3-phenoxyaniline; With hydrogenchloride; sodium nitrite; In water; at 0 ℃;

With tin(ll) chloride; In water; at 0 ℃;

DOI:10.1016/j.ejmech.2016.08.009

Reference yield: 76.0%

(3-phenoxyphenyl)hydrazine hydrochloride (109221-90-1) + methyl chloroformate (79-22-1) → methyl 2-(3-phenoxyphenyl) hydrazinecarboxylate (1189198-33-1)

Guidance literature:

With pyridine; dichloromethane; at 0 - 20 ℃; for 0.75h; Inert atmosphere;

DOI:10.1016/j.ejmech.2012.10.040

Reference yield: 25.0%

naltrexone Hydrochloride (16676-29-2) + (3-phenoxyphenyl)hydrazine hydrochloride (109221-90-1) → 17-(cyclopropylmethyl)-6,7-didehydro-4,5α-epoxy-13,14-dihydroxy-4'-phenoxyindolo[2',3':6,7]morphinan + 17-(cyclopropylmethyl)-6,7-didehydro-4,5α-epoxy-13,14-dihydroxy-6'-phenoxyindolo[2',3':6,7]morphinan

Guidance literature:

With hydrogenchloride; In methanol; for 5h; Heating;

DOI:10.1021/jm980083i

upstream raw materials:

3-phenoxyaniline

Downstream raw materials:

methyl 2-(3-phenoxyphenyl) hydrazinecarboxylate

Refernces

• 1、 Point, Vanessa,Pavan Kumar,Marc, Sylvain,Delorme, Vincent,Parsiegla, Goetz,Amara, Sawsan,Carrière, Frédéric,Buono, Gérard,Fotiadu, Frédéric,Canaan, Stéphane,Leclaire, Julien,Cavalier, Jean-Fran?ois. "Analysis of the discriminative inhibition of mammalian digestive lipases by 3-phenyl substituted 1,3,4-oxadiazol-2(3H)-ones". . p. 452 - 463. Retrieved 2013/02/23.