Technology Process of C22H22Cl2FN5O*CH2O2
There total 12 articles about C22H22Cl2FN5O*CH2O2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
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at 20 ℃;
for 1h;
Sonication;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: dmap / N,N-dimethyl-formamide / 18 h / 20 °C
2: potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 / dimethyl sulfoxide / 2 h / 80 °C / Inert atmosphere
3: hydrogenchloride / dichloromethane; 1,4-dioxane / 26 h / 0 - 40 °C
4: sodium carbonate; bis-triphenylphosphine-palladium(II) chloride / 1,2-dimethoxyethane; water / 16 h / 90 °C / Inert atmosphere
5: 1 h / 20 °C / Sonication
With
hydrogenchloride; dmap; bis-triphenylphosphine-palladium(II) chloride; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; potassium acetate; sodium carbonate;
In
1,4-dioxane; 1,2-dimethoxyethane; dichloromethane; water; dimethyl sulfoxide; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 / dimethyl sulfoxide / 2 h / 80 °C / Inert atmosphere
2: hydrogenchloride / dichloromethane; 1,4-dioxane / 26 h / 0 - 40 °C
3: sodium carbonate; bis-triphenylphosphine-palladium(II) chloride / 1,2-dimethoxyethane; water / 16 h / 90 °C / Inert atmosphere
4: 1 h / 20 °C / Sonication
With
hydrogenchloride; bis-triphenylphosphine-palladium(II) chloride; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; potassium acetate; sodium carbonate;
In
1,4-dioxane; 1,2-dimethoxyethane; dichloromethane; water; dimethyl sulfoxide;