2-(4-bromobenzoyl)-4-chlorophenyl dimethylcarbamate

Base Information

• Chemical Name: 2-(4-bromobenzoyl)-4-chlorophenyl dimethylcarbamate
• CAS No.: 1452841-77-8
• Molecular Formula: C₁₆H₁₃BrClNO₃
• Molecular Weight: 382.641
• Mol file: 1452841-77-8.mol

Synonyms:2-(4-bromobenzoyl)-4-chlorophenyl dimethylcarbamate

Chemical Property of 2-(4-bromobenzoyl)-4-chlorophenyl dimethylcarbamate

Chemical Property:

Purity/Quality:

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MSDS Files:

Useful:

Technology Process of 2-(4-bromobenzoyl)-4-chlorophenyl dimethylcarbamate

There total 2 articles about 2-(4-bromobenzoyl)-4-chlorophenyl dimethylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

O-(4-chlorophenyl)-N,N-dimethylcarbamate (7305-03-5) + 4-bromophenylglyoxylic acid (7099-87-8) → 2-(4-bromobenzoyl)-4-chlorophenyl dimethylcarbamate (1452841-77-8)

Guidance literature:

With ammonium peroxydisulfate; trifluorormethanesulfonic acid; palladium diacetate; In 1,2-dichloro-ethane; at 20 ℃; for 20h; Sealed tube;

DOI:10.1002/adsc.201200993

Reference yield:

para-bromoacetophenone (99-90-1) → 2-(4-bromobenzoyl)-4-chlorophenyl dimethylcarbamate (1452841-77-8)

Guidance literature:

Multi-step reaction with 2 steps

1: selenium(IV) oxide; pyridine

2: palladium diacetate; ammonium peroxydisulfate; trifluorormethanesulfonic acid / 1,2-dichloro-ethane / 20 h / 20 °C / Sealed tube

With pyridine; selenium(IV) oxide; ammonium peroxydisulfate; trifluorormethanesulfonic acid; palladium diacetate; In 1,2-dichloro-ethane;

DOI:10.1002/adsc.201200993

upstream raw materials:

O-(4-chlorophenyl)-N,N-dimethylcarbamate

4-bromophenylglyoxylic acid

para-bromoacetophenone

Refernces