2-AMINOBENZOIC ACID, [RING-14C(U)]

Base Information

• Chemical Name: 2-AMINOBENZOIC ACID, [RING-14C(U)]
• CAS No.: 104809-47-4
• Molecular Formula: C₇H₇NO₂
• Molecular Weight: 137.138
• Mol file: 104809-47-4.mol

Synonyms:ANTHRANILIC ACID, [RING-14C(U)];ANTHRANILIC ACID-RING-UL-14C;2-AMINOBENZOIC ACID, [RING-14C(U)];Benzoic acid, 2-amino-, labeled with carbon-14 (9CI);2-Aminobenzoic-ring-ul-14C acid

Chemical Property of 2-AMINOBENZOIC ACID, [RING-14C(U)]

Chemical Property:

• PSA: 63.32000
• LogP: 1.54820
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

ANTHRANILLIC ACID[RING-14C(U)] 95.00% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi,R
• Statements: 36
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-AMINOBENZOIC ACID, [RING-14C(U)]

There total 374 articles about 2-AMINOBENZOIC ACID, [RING-14C(U)] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

2-nitro-benzaldehyde (552-89-6) → 2-Aminobenzyl alcohol (5344-90-1) + anthranilic acid (118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4)

Guidance literature:

With graphitic carbon nitride; hydrazine hydrate; In water; at 90 ℃; for 4h; chemoselective reaction; Irradiation; Sealed tube; Green chemistry;

DOI:10.1002/asia.201800515

Reference yield: 37.0%

o-acetylamino-benzoic acid (89-52-1) → 2-Aminobenzyl alcohol (5344-90-1) + 2-acetamidobenzyl alcohol (20939-77-9) + anthranilic acid (118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4)

Guidance literature:

With samarium diiodide; water; In tetrahydrofuran; for 0.0333333h; Ambient temperature;

DOI:10.1246/cl.1993.1495

Reference yield: 27.0%

ortho-nitrobenzoic acid (552-16-9,104810-18-6) → 2-Aminobenzyl alcohol (5344-90-1) + anthranilic acid (118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4)

Guidance literature:

With hydrogenchloride; samarium; In methanol; for 0.166667h; Ambient temperature;

DOI:10.1248/cpb.42.402

upstream raw materials:

2-methyl-1H-indole

2-(Benzoylamino)benzoic Acid

phthalic anhydride

phthalimide

Downstream raw materials:

4-(2-carboxy-phenylhydrazono)-3-methyl-pentenedioic acid-anhydride

N-[8]quinolylmethylen-anthranilic acid

2-(4-amino-6-methyl-pyrimidin-2-ylamino)-benzoic acid

tryptanthrine

Refernces

• 1、 Sen Gupta, Susanta K.,Mishra, Sangeeta. "Kinetics of proton transfer between ortho substituted benzoic acids and the carbinol base of crystal violet in toluene. Ortho effect on the reactivity of benzoic acids in apolar aprotic solvents". . p. 4616 - 4623. Retrieved 2011.
• 2、 Pourjavadi, Ali,Kohestanian, Mohammad,Keshavarzi, Nahid. "Immobilization of Au nanoparticles on poly(glycidyl methacrylate)-functionalized magnetic nanoparticles for enhanced catalytic application in the reduction of nitroarenes and Suzuki reaction". . . Retrieved 2020.
• 3、 Wu, Gaochan,Gao, Yun,Kang, Dongwei,Huang, Boshi,Huo, Zhipeng,Liu, Huiqing,Poongavanam, Vasanthanathan,Zhan, Peng,Liu, Xinyong. "Design, synthesis and biological evaluation of tacrine-1,2,3-triazole derivatives as potent cholinesterase inhibitors". . p. 149 - 159. Retrieved 2018.
• 4、 Korbi, B. Haouas,Adhoum,Boujlel. "Electrochemical carboxylation of 2-iodoaromatic compounds". . p. 2557 - 2564. Retrieved 2004.
• 5、 Fan, Congbin,Liu, Gang,Pu, Shouzhi,Wang, Huaxin,Zhao, Heng. "A highly selective diarylethene fluorescence sensor of aluminum ion and its application". . . Retrieved 2021.
• 6、 Kalanpour, Nastaran,Nejati, Saeid,Keshipour, Sajjad. "Pd nanoparticles/graphene quantum dot supported on chitosan as a new catalyst for the reduction of nitroarenes to arylamines". . p. 1243 - 1250. Retrieved 2021.
• 7、 Kamal, Ahmed,Shankaraiah,Markandeya,Reddy, Ch. Sanjeeva. "An efficient selective reduction of aromatic azides to amines employing BF3·OEt2/NaI: Synthesis of pyrrolobenzodiazepines". . p. 1297 - 1300. Retrieved 2008.
• 8、 Pandarus, Valerica,Ciriminna, Rosaria,Beland, Francois,Pagliaro, Mario. "A new class of heterogeneous platinum catalysts for the chemoselective hydrogenation of nitroarenes". . p. 1306 - 1316. Retrieved 2011.
• 9、 Yatome, Chizuko,Fujimi, Kazuhiko,Ogawa, Toshihiko. "Effect of Inhibitors on Azo-Reduction of 4'-Dimethylaminoazobenzene-2-carboxylic Acid by Clostridium Diaphorase". . p. 2349 - 2351. Retrieved 1992.
• 10、 Nagaraja,Pasha. "Reduction of aryl nitro compounds with aluminium/NH4Cl: Effect of ultrasound on the rate of the reaction". . p. 7855 - 7856. Retrieved 1999.