t-butyl-4 cyclohexanecarboxaldehyde cis

Base Information

• Chemical Name: t-butyl-4 cyclohexanecarboxaldehyde cis
• CAS No.: 15763-61-8
• Molecular Formula: C₁₁H₂₀O
• Molecular Weight: 168.279
• Mol file: 15763-61-8.mol

Synonyms:t-butyl-4 cyclohexanecarboxaldehyde cis

Chemical Property of t-butyl-4 cyclohexanecarboxaldehyde cis

Chemical Property:

Purity/Quality:

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Technology Process of t-butyl-4 cyclohexanecarboxaldehyde cis

There total 17 articles about t-butyl-4 cyclohexanecarboxaldehyde cis which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

(3r,6r)-6-(tert-butyl)-1-oxaspiro[2.5]octane (18881-26-0) → cis-(4-tert-butylcyclohexyl)methanol (13004-06-3,20691-53-6,10601-39-5) + trans-(4-tert-butyl-cyclohexyl)-methanol (10601-39-5,20691-53-6,13004-06-3) + trans-4-(tert-butyl)cyclohexane-1-carbaldehyde (15763-62-9) + t-butyl-4 cyclohexanecarboxaldehyde cis (15763-61-8)

Guidance literature:

With hydrogen; Rh on carbon; In cyclohexane; at 20 ℃; under 760 Torr; Further byproducts given;

Reference yield: 34.0%

(3r,6r)-6-(tert-butyl)-1-oxaspiro[2.5]octane (18881-26-0) → 1-(tert-butyl)-4-methylcyclohexane (75736-66-2) + trans-(4-tert-butyl-cyclohexyl)-methanol (10601-39-5,20691-53-6,13004-06-3) + trans-4-(tert-butyl)cyclohexane-1-carbaldehyde (15763-62-9) + t-butyl-4 cyclohexanecarboxaldehyde cis (15763-61-8)

Guidance literature:

With hydrogen; Rh on carbon; In cyclohexane; at 20 ℃; under 760 Torr; Further byproducts given;

Reference yield: 20.0%

6-tert-Butyl-1-oxa-spiro[2.5]octane (7787-78-2) → cis-(4-tert-butylcyclohexyl)methanol (13004-06-3,20691-53-6,10601-39-5) + 4-tert-Butyl-1-methylcyclohex-1-en (3419-74-7) + 1-(tert-butyl)-4-methylcyclohexane (75736-66-2) + trans-(4-tert-butyl-cyclohexyl)-methanol (10601-39-5,20691-53-6,13004-06-3) + trans-4-(tert-butyl)cyclohexane-1-carbaldehyde (15763-62-9) + t-butyl-4 cyclohexanecarboxaldehyde cis (15763-61-8)

Guidance literature:

With hydrogen; Rh on carbon; In isopropyl alcohol; at 20 ℃; for 1h; under 760 Torr; Product distribution; examination of further catalysts, solvents, reaction time and epoxyde;

upstream raw materials:

6-tert-Butyl-1-oxa-spiro[2.5]octane

cis-(4-tert-butylcyclohexyl)methanol

(3r,6r)-6-(tert-butyl)-1-oxaspiro[2.5]octane

carbon monoxide

Downstream raw materials:

C₂₀H₃₀O

Refernces

• 1、 Muehling, Olaf,Wessig, Pablo. "Stereoselective synthesis of cyclopropanes based on a 1,2-chirality transfer". supporting information; experimental part. p. 7951 - 7960. Retrieved 2009/10/23.
• 2、 Accrombessi, Georges,Geneste, Patrick,Olive, Jean-Louis,Pavia, Andre Armand. "Hydrogenolyse en phase liquide des epoxydes du t-butyl-4 methylene-cyclohexane sur divers catalyseurs metalliques supportes". . p. 19 - 23. Retrieved 2007/10/02.