9-benzoyl-2-methylcarbazole

Base Information

• Chemical Name: 9-benzoyl-2-methylcarbazole
• CAS No.: 152499-78-0
• Molecular Formula: C₂₀H₁₅NO
• Molecular Weight: 285.345
• Mol file: 152499-78-0.mol

Synonyms:9-benzoyl-2-methylcarbazole

Chemical Property of 9-benzoyl-2-methylcarbazole

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 9-benzoyl-2-methylcarbazole

There total 1 articles about 9-benzoyl-2-methylcarbazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methyl-9H-carbazole (3652-91-3) + benzoyl chloride (98-88-4) → 9-benzoyl-2-methylcarbazole (152499-78-0)

Guidance literature:

With lithium hexamethyldisilazane; Yield given. Multistep reaction; 1.) THF, RT, 2 h, 2.) THF, a) -78 deg C, 1 h, b) RT, 12 h;

DOI:10.1080/00397919308011129

Reference yield: 82.0%

9-benzoyl-2-methylcarbazole (152499-78-0) → 9-benzoyl-2-bromomethylcarbazole (152499-79-1)

Guidance literature:

With N-Bromosuccinimide; Perbenzoic acid; In tetrachloromethane; for 20h; Heating;

DOI:10.1080/00397919308011129

Reference yield:

9-benzoyl-2-methylcarbazole (152499-78-0) → 2-Acetylamino-2-(9-benzoyl-9H-carbazol-2-ylmethyl)-malonic acid diethyl ester (152499-81-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 82 percent / N-bromosuccinimide, benzoyl peroxide / CCl₄ / 20 h / Heating

2: 1.) NaH / 1.) THF, RT, 1 h, 2.) THF, a) RT, 1 h, b) from 50 deg C to 60 deg C, 6 h

With N-Bromosuccinimide; Perbenzoic acid; sodium hydride; In tetrachloromethane;

DOI:10.1080/00397919308011129

upstream raw materials:

2-methyl-9H-carbazole

benzoyl chloride

Downstream raw materials:

9-benzoyl-2-bromomethylcarbazole

2-Acetylamino-2-(9-benzoyl-9H-carbazol-2-ylmethyl)-malonic acid diethyl ester

Refernces