(1R,2R)-2-(N,N-Dimethylamino)-1-(p-nitrophenyl)-1,3-propanediol

Base Information Edit

Chemical Name:(1R,2R)-2-(N,N-Dimethylamino)-1-(p-nitrophenyl)-1,3-propanediol
CAS No.:18867-45-3
Molecular Formula:C11H16 N2 O4
Molecular Weight:240.259
Hs Code.:2922199090
European Community (EC) Number:606-150-9
DSSTox Substance ID:DTXSID601189261
Nikkaji Number:J1.269.737F
Mol file:18867-45-3.mol

Synonyms:18867-45-3;(1R,2R)-2-(N,N-Dimethylamino)-1-(p-nitrophenyl)-1,3-propanediol;(1R,2R)-2-(dimethylamino)-1-(4-nitrophenyl)propane-1,3-diol;WKFXOUSFZMOKOH-GHMZBOCLSA-N;DTXSID601189261;(1R,2R)-1-(4-Nitrophenyl)-2-(dimethylamino)-1,3-propanediol;(1R,2R)-2-(Dimethylamino)-1-(4-nitrophenyl)-1,3-propanediol

Suppliers and Price of (1R,2R)-2-(N,N-Dimethylamino)-1-(p-nitrophenyl)-1,3-propanediol

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(1R,2R)-2-(N,N-DIMETHYLAMINO)-1-(PARA-NITROPHENYL)-1,3-PROPANEDIOL 95.00%
5MG
$ 498.85

Total 30 raw suppliers

Chemical Property of (1R,2R)-2-(N,N-Dimethylamino)-1-(p-nitrophenyl)-1,3-propanediol Edit

Chemical Property:

Vapor Pressure:9.35E-08mmHg at 25°C
Refractive Index:1.588
Boiling Point:418.6°Cat760mmHg
PKA:12.90±0.20(Predicted)
Flash Point:207°C
PSA：89.52000
Density:1.284g/cm³
LogP:1.07390
XLogP3:0.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:240.11100700
Heavy Atom Count:17
Complexity:246

Purity/Quality:

99%, ^*data from raw suppliers

(1R,2R)-2-(N,N-DIMETHYLAMINO)-1-(PARA-NITROPHENYL)-1,3-PROPANEDIOL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)C(CO)C(C1=CC=C(C=C1)[N+](=O)[O-])O
Isomeric SMILES:CN(C)[C@H](CO)[C@@H](C1=CC=C(C=C1)[N+](=O)[O-])O
Use Description (1R,2R)-2-(N,N-Dimethylamino)-1-(p-nitrophenyl)-1,3-propanediol, often referred to as pindolol, finds important applications in various fields. In the medical field, pindolol serves as a non-selective beta-adrenergic antagonist and is commonly used to treat hypertension and angina. Its unique properties as a partial beta-blocker allow it to help regulate blood pressure while also mitigating some of the potential side effects associated with full beta-blockers. In addition to its cardiovascular applications, pindolol has also been studied in the field of psychiatry, where it is used as an augmentation therapy for depression and anxiety disorders. By acting as a serotonin receptor antagonist, it can enhance the effectiveness of other antidepressant medications. Overall, pindolol plays a pivotal role in improving patient health and well-being in both cardiovascular and psychiatric treatments.

Technology Process of (1R,2R)-2-(N,N-Dimethylamino)-1-(p-nitrophenyl)-1,3-propanediol

There total 1 articles about (1R,2R)-2-(N,N-Dimethylamino)-1-(p-nitrophenyl)-1,3-propanediol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%