5-METHYLISOPTHALIC ACID DIMETHYLESTER

Base Information

• Chemical Name: 5-METHYLISOPTHALIC ACID DIMETHYLESTER
• CAS No.: 17649-58-0
• Molecular Formula: C11H12 O4
• Molecular Weight: 208.214
• Hs Code.: 2917399090
• Mol file: 17649-58-0.mol

Synonyms:1,3-Benzenedicarboxylicacid, 5-methyl-, dimethyl ester (9CI); Isophthalic acid, 5-methyl-, dimethyl ester(7CI,8CI); Dimethyl 5-methylisophthalate

Chemical Property of 5-METHYLISOPTHALIC ACID DIMETHYLESTER

Chemical Property:

• PSA: 52.60000
• LogP: 1.56820

Purity/Quality:

98%Min ^*data from raw suppliers

5-Methylisopathalicaciddimethylester 98 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-METHYLISOPTHALIC ACID DIMETHYLESTER

There total 6 articles about 5-METHYLISOPTHALIC ACID DIMETHYLESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.72%

methanol (67-56-1) + 5-methylisophthalic aicd (499-49-0) → 5-Methylisophthalsaeure-dimethylester (17649-58-0)

Guidance literature:

With sulfuric acid; Inert atmosphere; Reflux;

Reference yield: 80.0%

dihydroxy-methyl-borane (13061-96-6) + dimethyl 5-bromoisophthalate (51760-21-5) → 5-Methylisophthalsaeure-dimethylester (17649-58-0)

Guidance literature:

With potassium phosphate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In toluene; at 90 ℃; for 18h; Inert atmosphere;

DOI:10.1016/j.ejmech.2018.11.068

Reference yield:

methanol (67-56-1) + 5-methylisophthaloyl dichloride (13438-29-4) → 5-Methylisophthalsaeure-dimethylester (17649-58-0)

Guidance literature:

With triethylamine; In tetrahydrofuran;

upstream raw materials:

5-methylisophthalic aicd

methanol

dihydroxy-methyl-borane

dimethyl 5-bromoisophthalate

Downstream raw materials:

1,3-bis-(hydroxymethyl)-5-methylbenzene

5-methylbenzene-1,3-dicarboxaldehyde

Refernces

• 1、 Huang, Xianqiang,Liu, Qingzhi,Liu, Shixi,Ma, Shengqian,Nafady, Ayman,Niu, Zheng,Ren, Junyu,Tsai, Chen-Yen,Ye, Yingxiang. "Second-Sphere Interaction Promoted Turn-On Fluorescence for Selective Sensing of Organic Amines in a TbIII-based Macrocyclic Framework". . p. 23705 - 23712. Retrieved 2021.
• 2、 Liu, Xiao-Fei,Guo, Xiao-Qing,Wang, Rui,Liu, Qing-Chao,Li, Zhong-Jun,Zang, Shuang-Quan,Mak, Thomas C. W.. "Manganese cluster-based MOF as efficient polysulfide-trapping platform for high-performance lithium-sulfur batteries". . p. 2838 - 2844. Retrieved 2019.
• 3、 Huang, Xinghua,Huang, Shiyao,Zhai, Baoqi,Zhang, Yu,Xu, Yanan,Wang, Qiaochun. "Slipping synthesis of cucurbit[7]uril-based [2]rotaxane in organic environment". . p. 6414 - 6417. Retrieved 2012.
• 4、 -. "COMPOUND, POLYMER, PATTERN FORMING MATERIAL, AND MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE". . . Retrieved 2021/03/13.