1,3-BenzenediMethanol, 5-Methyl

Base Information

• Chemical Name: 1,3-BenzenediMethanol, 5-Methyl
• CAS No.: 27711-63-3
• Molecular Formula: C9H12O2
• Molecular Weight: 152.193
• Mol file: 27711-63-3.mol

Synonyms:a1,a3-Mesitylenediol (8CI);(3-Hydroxymethyl-5-methylphenyl)methanol;NSC 243674;(5-Methylbenzene-1,3-diyl)dimethanol;

Chemical Property of 1,3-BenzenediMethanol, 5-Methyl

Chemical Property:

• Vapor Pressure: 0.000293mmHg at 25°C
• Melting Point: 40 °C
• Refractive Index: 1.573
• Boiling Point: 308.5 °C at 760 mmHg
• PKA: 14.27±0.10(Predicted)
• Flash Point: 152.6 °C
• PSA: 40.46000
• Density: 1.141 g/cm³
• LogP: 0.97960

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,3-BenzenediMethanol, 5-Methyl

There total 7 articles about 1,3-BenzenediMethanol, 5-Methyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

→ 1,3-bis-(hydroxymethyl)-5-methylbenzene (27711-63-3)

Guidance literature:

With diborane; In tetrahydrofuran; at 0 - 20 ℃; for 49h; Inert atmosphere;

Reference yield:

5-Methylisophthalsaeure-dimethylester (17649-58-0) → 1,3-bis-(hydroxymethyl)-5-methylbenzene (27711-63-3)

Guidance literature:

With potassium borohydride; lithium chloride; In tetrahydrofuran; for 6h; Reflux;

DOI:10.1080/00304940809458112

Reference yield:

1,3-bis-acetoxymethyl-5-methyl-benzene (854752-44-6) → 1,3-bis-(hydroxymethyl)-5-methylbenzene (27711-63-3)

Guidance literature:

With potassium carbonate;

upstream raw materials:

1,3-bis-acetoxymethyl-5-methyl-benzene

1,3-bis-chloromethyl-5-methyl-benzene

water

3,5-bis(bromomethyl)toluene

Downstream raw materials:

3,5-bis(2-hydroxy-5-methylphenylmethyl)toluene

5-methylbenzene-1,3-dicarboxaldehyde

17-tert-butyl-26,27,28-trihydroxy-5,11,23-trimethylcalix<4>arene

[3-(tert-butyl-dimethyl-silanyloxymethyl)-5-methyl-phenyl]-methanol

Refernces

• 1、 Mei, Yu-Hua,Luo, Yu,Lu, Wei. "An efficient synthesis of 3,5-bis(2-cyanoisopropyl)toluene". experimental part. p. 487 - 489. Retrieved 2009/04/11.