2-Bromo-4-ethoxypyridine

Base Information

• Chemical Name: 2-Bromo-4-ethoxypyridine
• CAS No.: 17117-13-4
• Molecular Formula: C7H8 Br N O
• Molecular Weight: 202.04852
• Hs Code.: 2933399090
• Mol file: 17117-13-4.mol

Synonyms:2-Bromo-4-ethoxypyridine

Chemical Property of 2-Bromo-4-ethoxypyridine

Chemical Property:

• Vapor Pressure: 0.0407mmHg at 25°C
• Melting Point: 38 °C
• Refractive Index: 1.534
• Boiling Point: 247.3°Cat760mmHg
• PKA: 2.10±0.10(Predicted)
• Flash Point: 103.4°C
• PSA: 22.12000
• Density: 1.449g/cm³
• LogP: 2.24280
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

NLT 98% ^*data from raw suppliers

2-Bromo-4-ethoxypyridine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Bromo-4-ethoxypyridine

There total 2 articles about 2-Bromo-4-ethoxypyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-bromo-4-nitropyridine (6945-67-1) → 2-bromo-4-ethoxy-pyridine (17117-13-4)

Guidance literature:

With sodium ethanolate; In ethanol;

Reference yield:

→ 2-bromo-4-ethoxy-pyridine (17117-13-4)

Guidance literature:

2-Brom-4-hydroxy-pyridin, ether. Diazoethan-Lsg. (2Mol);

Reference yield:

2-bromo-4-ethoxy-pyridine (17117-13-4) + 1-phenylimidazol-4-amine hydrochloride (1821666-85-6) → 4-ethoxy-N-(1-phenylimidazol-4-yl)pyridin-2-amine

Guidance literature:

With [2-(di-tert-butylphosphino)-2′,4′,6′-triisopropyl-1,1′-biphenyl][2-((2-aminoethyl)phenyl)]palladium(II) chloride; sodium t-butanolate; In 1,4-dioxane; at 120 ℃; for 0.5h; Inert atmosphere; Microwave irradiation;

upstream raw materials:

2-bromo-4-nitropyridine

Downstream raw materials:

4-ethoxy-2-(3-nitrophenyl)pyridine

2-(3,5-bis-(4-fluoro-phenyl)-(1,2,4)triazol-1-yl)-1-(4-(4-ethoxy-pyridin-2-yl)-piperazin-1-yl)-ethanone

Refernces