M-BROMOBENZOYL BROMIDE

Base Information

• Chemical Name: M-BROMOBENZOYL BROMIDE
• CAS No.: 16331-47-8
• Molecular Formula: C7H4 Br2 O
• Molecular Weight: 263.916
• Hs Code.: 2916399090
• Mol file: 16331-47-8.mol

Synonyms:Benzoylbromide, p-bromo- (8CI); 4-Bromobenzoyl bromide

Chemical Property of M-BROMOBENZOYL BROMIDE

Chemical Property:

• PSA: 17.07000
• LogP: 2.98420

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of M-BROMOBENZOYL BROMIDE

There total 5 articles about M-BROMOBENZOYL BROMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

4-bromo-benzaldehyde (1122-91-4) → 4-bromobenzoyl bromide (16331-47-8)

Guidance literature:

With sulfurous dibromide; at 80 - 90 ℃; for 3h;

Reference yield:

para-bromoacetophenone (99-90-1) → 4-bromobenzoyl bromide (16331-47-8)

Guidance literature:

With aluminum (III) chloride; bromine; In tetrahydrofuran; at 0 ℃; for 0.333333h;

DOI:10.1016/j.ejmech.2013.11.020

Reference yield:

→ 4-bromobenzoyl bromide (16331-47-8)

Guidance literature:

With phosphorus pentabromide; benzene;

upstream raw materials:

4-bromo-benzaldehyde

Oxalyl bromide

para-bromoacetophenone

4-Bromobenzoic acid

Downstream raw materials:

4-(4-bromo-benzoyloximethyl)-2,2-dimethyl-[1,3]dioxolane

cis-5-(4-bromo-benzoyloxy)-2-phenyl-[1,3]dioxane

1-[(4-bromophenyl)carbonyl]piperazine

Refernces

• 1、 Li, Jing-Ran,Li, Dong-Dong,Wang, Rong-Rong,Sun, Jian,Dong, Jing-Jun,Du, Qian-Ru,Fang, Fei,Zhang, Wei-Ming,Zhu, Hai-Liang. "Design and synthesis of thiazole derivatives as potent FabH inhibitors with antibacterial activity". . p. 438 - 447. Retrieved 2014/03/21.