C₂₁H₂₅ClFN₅O₄

Base Information

• Chemical Name: C₂₁H₂₅ClFN₅O₄
• CAS No.: 1048675-61-1
• Molecular Formula: C₂₁H₂₅ClFN₅O₄
• Molecular Weight: 465.912
• Mol file: 1048675-61-1.mol

Synonyms:C₂₁H₂₅ClFN₅O₄

Chemical Property of C₂₁H₂₅ClFN₅O₄

Chemical Property:

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Technology Process of C₂₁H₂₅ClFN₅O₄

There total 1 articles about C₂₁H₂₅ClFN₅O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-[(4-amino-1H-pyrazole-3-carbonyl)amino]piperidine-1-carboxylic acid tert-butyl ester (844443-81-8) + 2-chloro-6-fluorobenzoic acid (434-75-3) → C21H25ClFN5O4 (1048675-61-1)

Guidance literature:

With 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 16h;

DOI:10.1021/jm800382h

Reference yield:

C21H25ClFN5O4 (1048675-61-1) → 4-(2-chloro-6-fluorobenzoylamino)-1H-pyrazole-3-carboxylic acid piperidin-4-ylamide

Guidance literature:

With hydrogenchloride; In ethyl acetate; at 20 ℃; for 1h;

DOI:10.1021/jm800382h

upstream raw materials:

4-[(4-amino-1H-pyrazole-3-carbonyl)amino]piperidine-1-carboxylic acid tert-butyl ester

2-chloro-6-fluorobenzoic acid

Refernces