4,4'-Bipiperidine

Base Information

• Chemical Name: 4,4'-Bipiperidine
• CAS No.: 15336-72-8
• Molecular Formula: C10H20 N2
• Molecular Weight: 168.282
• Hs Code.: 2933399090
• European Community (EC) Number: 683-647-7
• DSSTox Substance ID: DTXSID80352918
• Nikkaji Number: J313.890I
• Wikidata: Q82130339
• Mol file: 15336-72-8.mol

Synonyms:4,4'-bipiperidine

Chemical Property of 4,4'-Bipiperidine

Chemical Property:

• Melting Point: 169.0 to 173.0 °C
• Boiling Point: 278.6±8.0 °C(Predicted)
• PKA: 10.68±0.10(Predicted)
• PSA: 24.06000
• Density: 0.942±0.06 g/cm3(Predicted)
• LogP: 1.64320
• Solubility.: soluble in Methanol
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 168.162648646
• Heavy Atom Count: 12
• Complexity: 108

Purity/Quality:

98%,99%, ^*data from raw suppliers

4,4''-Bipiperidine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 41
• Safety Statements: 26-39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CNCCC1C2CCNCC2

Technology Process of 4,4'-Bipiperidine

There total 7 articles about 4,4'-Bipiperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4,4'-bipiperidine dihydrochloride (78619-84-8) → 4,4'-bipiperidine (15336-72-8)

Guidance literature:

With sodium hydroxide;

DOI:10.1021/jm050498l

Reference yield:

4,4'-bipyridine (553-26-4) → 4,4'-bipiperidine (15336-72-8)

Guidance literature:

With hydrogenchloride; platinum(IV) oxide; Hydrogenation;

Reference yield:

pyridine (110-86-1) → 4,4'-bipiperidine (15336-72-8)

Guidance literature:

With sulfuric acid; elektrochem. Reduktion an einer Blei-Kathode;

DOI:10.1039/jr9530003872

upstream raw materials:

pyridine

4,4'-bipyridine

1,1'-diacetyl-dodecahydro-[4,4']bipyridinyl

4,4'-bipiperidine dihydrochloride

Downstream raw materials:

1,1'-dibenzyl-dodecahydro-[4,4']bipyridinyl

1-Benzoyl-dodecahydro-[4,4']bipyridyl

1,1'-Dibenzoyl-dodecahydro-[4,4']bipyridyl

4,4'-bipyridine

Refernces

• 1、 Forostyan,Forostyan. "-". . . Retrieved 1976.
• 2、 -. "17 Beta-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases". Page 21. . Retrieved 2008/06/13.