4,4'-Bipiperidine dihydrochloride

Base Information

• Chemical Name: 4,4'-Bipiperidine dihydrochloride
• CAS No.: 78619-84-8
• Molecular Formula: C10H20N2^.2(HCl)
• Molecular Weight: 241.204
• Hs Code.: 2933399090
• European Community (EC) Number: 278-958-6
• Mol file: 78619-84-8.mol

Synonyms:4,4'-Bipiperidine dihydrochloride;78619-84-8;4,4'-Bipiperidyl dihydrochloride;4,4'-Bipiperidine diHCl;SCHEMBL2361641;4,4'-bipiperidinedihydrochloride;MQKBVVIPCLTENX-UHFFFAOYSA-N;MFCD00005998;AKOS015844816;4,4'-Bipiperidyl dihydrochloride, 97%;AS-61262;4-piperidin-4-ylpiperidine;dihydrochloride;CS-0155214;FT-0617007;NS00062327;D84219;A839461

Chemical Property of 4,4'-Bipiperidine dihydrochloride

Chemical Property:

• Melting Point: >300 °C(lit.)
• Boiling Point: 278.6 ºC at 760 mmHg
• Flash Point: 151.5 ºC
• PSA: 24.06000
• LogP: 2.44520
• Storage Temp.: Inert atmosphere,Room Temperature
• Sensitive.: Hygroscopic
• Solubility.: 1 M HCl: 25 mg/mL, clear
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 240.1160041
• Heavy Atom Count: 14
• Complexity: 108

Purity/Quality:

98%,99%, ^*data from raw suppliers

4,4′-Bipiperidyl dihydrochloride 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1CNCCC1C2CCNCC2.Cl.Cl
• Uses: 4,4′-Bipiperidyl dihydrochloride was used in the synthesis of organomodified montmorillonite (MMT) clay.

Technology Process of 4,4'-Bipiperidine dihydrochloride

There total 2 articles about 4,4'-Bipiperidine dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 4,4'-bipiperidine dihydrochloride (78619-84-8)

Guidance literature:

Reference yield:

→ (E)-3-(3-quinolyl)-2-propenoic acid hydrochloride + 4,4'-bipiperidine dihydrochloride (78619-84-8)

Guidance literature:

Reference yield: 96.2%

4,4'-bipiperidine dihydrochloride (78619-84-8) + benzyl chloroformate (501-53-1,94274-21-2) → decahydro-[4,4']bipyridyl-1-carboxylic acid benzyl ester (109397-72-0)

Guidance literature:

With sodium hydroxide; bromophenol blue; In methanol; water; toluene; at 20 ℃; for 4h;

Downstream raw materials:

4,4'-bipiperidine

1-tert-butoxycarbonyl-4,4'-bipiperidine

decahydro-[4,4']bipyridyl-1-carboxylic acid benzyl ester

C₂₃H₃₅N₃O₃

Refernces

• 1、 -. "Sodium channel drugs and uses". . . Retrieved 2008/06/13.