(+)-α-cuprenene

Base Information

• Chemical Name: (+)-α-cuprenene
• CAS No.: 135096-31-0
• Molecular Formula: C₁₅H₂₄
• Molecular Weight: 204.356
• Mol file: 135096-31-0.mol

Synonyms:(+)-α-cuprenene

Chemical Property of (+)-α-cuprenene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+)-α-cuprenene

There total 4 articles about (+)-α-cuprenene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

farnesyl pyrophosphate (372-97-4,13058-04-3,25744-33-6,27248-37-9,27248-38-0,40716-68-5) → (E)-β-farnesene (18794-84-8) + trichodiene (28624-60-4) + (+)-α-cuprenene (135096-31-0) + (+)-(R)-isochamigrene

Guidance literature:

With Tris buffer pH 7.8; 2-hydroxyethanethiol; magnesium chloride; at 30 ℃; for 16h; Further byproducts given. Title compound not separated from byproducts; D₉₈E mutant of recombinant F_. sporotrichioides trichodiene synthase;

DOI:10.1021/ja961897w

Reference yield:

(-)-microbiotol (78361-92-9) → (+)-α-cuprenene (135096-31-0)

Guidance literature:

With trichlorophosphate; In pyridine; at 20 ℃; for 1h;

DOI:10.1016/S0031-9422(98)00152-6

Reference yield:

farnesyl pyrophosphate (372-97-4,13058-04-3,25744-33-6,27248-37-9,27248-38-0,40716-68-5) → (R)-(Z)-α-bisabolene (70286-33-8) + (-)-β-bisabolene (20377-48-4) + trichodiene (28624-60-4) + (+)-α-cuprenene (135096-31-0)

Guidance literature:

With Tris buffer; at 30 ℃; for 16h; Yield given. Title compound not separated from byproducts; Y₃₀₅T mutant of recombinant Fusarium sporotrichioides trichodiene synthase;

DOI:10.1021/ja953751n

upstream raw materials:

farnesyl pyrophosphate

(-)-microbiotol

Refernces

• 1、 Cane, David E.,Xue, Qun,Van Epp, James E.,Tsantrizos, Youla S.. "Enzymatic formation of isochamigrene, a novel sesquiterpene, by alteration of the aspartate-rich region of trichodiene synthase". . p. 8499 - 8500. Retrieved 1996.