1,2,3,4-Tetrahydro-1,6-naphthyridine

Base Information

• Chemical Name: 1,2,3,4-Tetrahydro-1,6-naphthyridine
• CAS No.: 13623-84-2
• Molecular Formula: C8H10 N2
• Molecular Weight: 134.18
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID20475913
• Wikidata: Q72506290
• Mol file: 13623-84-2.mol

Synonyms:1,2,3,4-TETRAHYDRO-1,6-NAPHTHYRIDINE;13623-84-2;1,2,3,4-Tetrahydro-[1,6]naphthyridine;1,6-Naphthyridine, 1,2,3,4-tetrahydro-;MFCD08234763;F1957-0068;SCHEMBL987978;SCHEMBL21383385;DTXSID20475913;AKOS000275961;5,6,78-tetrahydro-1,6-naphthyridine;AB43638;CS-W006210;SB11123;SY023238;1,6-Naphthyridine, 1,2,3,4-tetrahydro;AM20050798;FT-0660738;EN300-238018;A807045;1,2,3,4-tetrahydro-1,6-naphthyridine, AldrichCPR

Chemical Property of 1,2,3,4-Tetrahydro-1,6-naphthyridine

Chemical Property:

• Melting Point: 155-158 °C(Solv: benzene (71-43-2))
• Boiling Point: 284.3±9.0 °C(Predicted)
• PKA: 9.89±0.20(Predicted)
• PSA: 24.92000
• Density: 1.068±0.06 g/cm3(Predicted)
• LogP: 1.57770
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 134.084398327
• Heavy Atom Count: 10
• Complexity: 114

Purity/Quality:

98%,99%, ^*data from raw suppliers

1,2,3,4-Tetrahydro-1,6-naphthyridine 95% ^*data from reagent suppliers

Safty Information:

• Statements: 36
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC2=C(C=CN=C2)NC1
• Uses: 1,2,3,4-Tetrahydro-1,6-naphthyridine is used to enhance the catalytic activity of 4-(dialkylamino)pyridines for acetylation by conformational fixation.

Technology Process of 1,2,3,4-Tetrahydro-1,6-naphthyridine

There total 7 articles about 1,2,3,4-Tetrahydro-1,6-naphthyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,6-naphthyridine (253-72-5) → 1,2,3,4-tetrahydro-1,6-naphthyridine (13623-84-2)

Guidance literature:

With methanol; Lindlar's catalyst; Hydrogenation;

Reference yield:

5-chloro-[1,6]naphthyridine (23616-32-2) → 1,2,3,4-tetrahydro-1,6-naphthyridine (13623-84-2)

Guidance literature:

With methanol; Lindlar's catalyst; Hydrogenation;

Reference yield:

3-(4-nitro-1-oxy-[3]pyridyl)-propionic acid (108129-68-6) → 1,2,3,4-tetrahydro-1,6-naphthyridine (13623-84-2)

Guidance literature:

With hydrogenchloride; zinc;

upstream raw materials:

1,6-naphthyridine

3-(4-nitro-1-oxy-[3]pyridyl)-propionic acid

5-chloro-[1,6]naphthyridine

methanol

Downstream raw materials:

1,6-naphthyridine