N-O-NITROPHENYLSULFENYL-L-ISOLEUCINE*DCH A

Base Information

• Chemical Name: N-O-NITROPHENYLSULFENYL-L-ISOLEUCINE*DCH A
• CAS No.: 10382-52-2
• Molecular Formula: C48H76N6O8S2
• Molecular Weight: 929.28244
• Mol file: 10382-52-2.mol

Synonyms:N-O-NITROPHENYLSULFENYL-L-ISOLEUCINE*DCH A;N-o-NPS-L-Isoleucine, dicyclohexylammonium salt N-o-Nitrophenylsulfenyl-L-isoleucine, dicyclohexylammonium salt

Chemical Property of N-O-NITROPHENYLSULFENYL-L-ISOLEUCINE*DCH A

Chemical Property:

• Melting Point: 188.0 to 192.0 °C
• PSA: 132.48000
• LogP: 7.23720
• Solubility.: almost transparency in Methanol

Purity/Quality:

98%,99%, ^*data from raw suppliers

N-2-Nitrophenylsulfenyl-L-isoleucine Dicyclohexylammonium Salt ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-O-NITROPHENYLSULFENYL-L-ISOLEUCINE*DCH A

There total 1 articles about N-O-NITROPHENYLSULFENYL-L-ISOLEUCINE*DCH A which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ (S)-3-Methyl-2-(2-nitro-phenylsulfanylamino)-pentanoic acid; compound with dicyclohexyl-amine (10382-52-2)

Guidance literature:

L-Isoleucin, o-Nitrophenylsulfenylthiocyanat, AgNO3, DCHA;

DOI:10.1039/j39700002180

Reference yield: 94.0%

2-nitrophenylsulphenyl-L-isoleucine dicyclohexylammonium salt (10382-52-2) + methoxycarbonylmethylamine (616-34-2) → [(2S,3S)-3-Methyl-2-(2-nitro-phenylsulfanylamino)-pentanoylamino]-acetic acid methyl ester (60345-56-4)

Guidance literature:

With dicyclohexyl-carbodiimide; In dichloromethane; at -10 ℃; for 0.333333h;

Reference yield: 93.0%

(S)-alanine ethyl ester hydrochloride (1115-59-9) + 2-nitrophenylsulphenyl-L-isoleucine dicyclohexylammonium salt (10382-52-2) → Nps-Ile-Ala-OEt (97305-67-4)

Guidance literature:

With dicyclohexyl-carbodiimide; In chloroform; 1)-10 deg C, 2 h; 2) 2 h, room temperature;

Downstream raw materials:

(S)-2-[(2S,3S)-3-Methyl-2-(2-nitro-phenylsulfanylamino)-pentanoylamino]-propionic acid methyl ester

Nps-Ile-Ala-OEt

Nps-Ile-Met-OEt

Nps-Ile-Ser-Leu-OMe

Refernces