2-CYCLOHEXEN-1-ONE DIMETHYLKETAL

Base Information

• Chemical Name: 2-CYCLOHEXEN-1-ONE DIMETHYLKETAL
• CAS No.: 1728-18-3
• Molecular Formula: C8H14 O2
• Molecular Weight: 142.198
• Hs Code.: 2911000000
• Mol file: 1728-18-3.mol

Synonyms:2-Cyclohexen-1-one,dimethyl acetal (7CI); 3,3-Dimethoxycyclohexene

Chemical Property of 2-CYCLOHEXEN-1-ONE DIMETHYLKETAL

Chemical Property:

• Boiling Point: 67 °C / 21mmHg
• Flash Point: 49.8oC
• PSA: 18.46000
• Density: 0.98
• LogP: 1.71560

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Cyclohexen-1-one Dimethylketal ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-CYCLOHEXEN-1-ONE DIMETHYLKETAL

There total 4 articles about 2-CYCLOHEXEN-1-ONE DIMETHYLKETAL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cyclohexenone (930-68-7) + trimethyl orthoformate (149-73-5) → dimethylacetal of cyclohexenone (1728-18-3)

Guidance literature:

With sodium methylate; In methanol; Ambient temperature;

DOI:10.1021/jo00224a038

Reference yield:

α-bromocyclohexanone dimethyl ketal (1728-17-2) → dimethylacetal of cyclohexenone (1728-18-3)

Guidance literature:

With sodium methylate; dimethyl sulfoxide;

DOI:10.1021/jo01018a001

Reference yield:

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) → dimethylacetal of cyclohexenone (1728-18-3)

Guidance literature:

Multi-step reaction with 2 steps

1: Br₂

2: NaOMe, DMSO

With bromine; sodium methylate; dimethyl sulfoxide;

DOI:10.1021/jo01018a001

upstream raw materials:

cyclohexenone

trimethyl orthoformate

α-bromocyclohexanone dimethyl ketal

cyclohexanone

Downstream raw materials:

3-(2-oxo-2-phenylethyl)cyclohexanone

(3R)-3-isobutylcyclohexanone

(S)-3-isobutyl-cyclohexanone

(R)-3-ethylcyclohexanone

Refernces

• 1、 Taskinen, Esko,Nummelin, Kari. "Thermodynamics of Vinyl Ethers. 31. Isomer Equilibria in Some Six- and Seven-Membered Cyclic Dienes". . p. 4844 - 4847. Retrieved 2007/10/02.