1728-17-2Relevant articles and documents
Geminal acylation of α-heterosubstituted cyclohexanones and their ketals
Pottie, Ian R.,Crane, Sheldon N.,Gosse, Anna Lee,Miller, David O.,Burnell, D. Burnell
body text, p. 1118 - 1124 (2011/01/09)
Geminal acylation of derivatives of cyclohexanone with Br, Cl, F, and OCH3 in the α position, and of their corresponding dimethyl ketals, could not be accomplished to a significant extent following published procedures. The transformation was a
A New α-Iodination of Ketones Using Iodine-Ammonium Cerium(IV) Nitrate in Alcohol or Acetic Acid
Horiuchi, C. Akira,Kiji, Shinji
, p. 421 - 426 (2007/10/03)
The direct α-iodination of various ketones using iodine-ammonium cerium(IV) nitrate in acetic acid or alcohol gave the corresponding α-iodo ketones in high yields. The effect of cerium salt on the iodination of ketones, and the iodination of 5α-cholestan-3-one using several methods are also discussed. In the reaction of 3,3,5-trimethylcyclohexanone and unsymmetrical ketones, such as 2-hexanone and 2-heptanone, using methanol, ethanol, 1-propanol, and 2-propanol, the regioselective iodination product was obtained. In the case of bromination, the reaction of ketones with bromine and ammonium cerium(IV) nitrate also yielded the corresponding α-bromo ketones.
STEREOCHEMICAL STUDIES-XXVI CONFORMATIONAL EQUILIBRIA OF KETALS OF 2-SUBSTITUTED CYCLOHEXANONES
Mursakulov, Ismail G.,Guseinov, M. M.,Kasumov, N. K.,Zefirov, Nikolai S.,Samoshin, V. V.,Chalenko, E. G.
, p. 2213 - 2220 (2007/10/02)
The positions of the conformational equilibria in a series of 2-substituted cyclohexanone ketals have been determined by 1H NMR.For the ethylene ketals 6 the equatorial conformer has been found to be enthalpically preferred.The other ketal syst
