1728-18-3

Basic information

• Product Name: 2-CYCLOHEXEN-1-ONE DIMETHYLKETAL
• Synonyms: cyclohexenonedimethylketal;2-CYCLOHEXEN-1-ONE DIMETHYLKETAL;3,3-DIMETHOXY-1-CYCLOHEXENE;2-CYCLOHEXEN-1-ONE DIMETHYLKETAL 85+%;2-Cyclohexen-1-one dimethyl acetal;3,3-Dimethoxycyclohexene
• CAS NO: 1728-18-3
• Molecular Formula: C₈H₁₄O₂
• Molecular Weight: 142.2
• Mol File: 1728-18-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 67 °C / 21mmHg
• Appearance: /
• Density: 0.98
• CAS DataBase Reference: 2-CYCLOHEXEN-1-ONE DIMETHYLKETAL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CYCLOHEXEN-1-ONE DIMETHYLKETAL(1728-18-3)
• EPA Substance Registry System: 2-CYCLOHEXEN-1-ONE DIMETHYLKETAL(1728-18-3)

Safety Data

• RIDADR: 3271
• HazardClass: 3
• PackingGroup: III
• Hazardous Substances Data: 1728-18-3(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 930-68-7 cyclohexenone 
• 108-94-1 cyclohexanone 
• 1728-17-2 α-bromocyclohexanone dimethyl ketal 
• 149-73-5 trimethyl orthoformate 

Downstream Products

• 39178-69-3 rac-3-butylcyclohexanone 
• 220617-60-7 (S)-6-[(3aR,5S,6S,6aR)-5-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-6-vinyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl]-cyclohex-2-enone 
• 20795-53-3 (R)-3-phenylcyclohexanone 
• 57344-86-2 (S)-3-phenylcyclohexanone 
• 168038-38-8 (R)-(-)-3-(2-phenylethyl)cyclohexanone 
• 211998-39-9 (S)-3-Ethyl-1-methoxy-cyclohexene 
• 22461-89-8 (R)-3-ethylcyclohexanone 
• 22461-89-8 3-ethylcyclohexanone 
• 72746-41-9 (R)-3-butylcyclohexanone 
• 39178-69-3 (S)-3-butylcyclohexan-1-one 
• 73959-39-4 (3R)-3-isobutylcyclohexanone 
• 73959-38-3 (S)-3-isobutyl-cyclohexanone 
• 94483-98-4 (Z) 1-methoxy-2-cyclohexenyl 
• 2161-90-2 1-methoxy-1,3-cyclohexadiene 

Relevant articles and documents

Cerium-free Luche reduction directed by rehydrated alumina

A 1,2-regioselective reduction of α,β-unsaturated ketones to their corresponding allylic alcohols is accomplished with NaBH4 in the presence of acidic activated alumina rehydrated to the Brockmann II grade by adding 3 % w/w water. The substrate scope includes eight ketones reduced in high regio- and diastereoselectivity to their corresponding allylic alcohols. This is the first example of the strategy of systematically tuning the surface chemistry of alumina via partial rehydration in order to modulate selectivity in a reaction. Alumina is an appealing alternative to the common Luche reduction additive, CeCl3, from the perspective of cost and procedural simplicity.