Technology Process of C15H18O3
There total 4 articles about C15H18O3 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: n-BuLi; DIPA; HMPA / tetrahydrofuran; hexane / 0.33 h / -78 °C
1.2: tetrahydrofuran / -78 - 20 °C
2.1: 87 percent / xylene / 18 h / 180 °C
With
N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; diisopropylamine;
In
tetrahydrofuran; hexane; xylene;
2.1: Claisen-Ireland rearrangement reaction;
DOI:10.1055/s-2007-967937
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: Mg; bromine; HgCl2 / tetrahydrofuran / 2.5 h / -5 °C
1.2: 92 percent / CuCN / tetrahydrofuran / 0.25 h / -20 °C
2.1: 95 percent / DIAD; Ph3P / diethyl ether / 0.5 h / 0 °C
3.1: n-BuLi; DIPA; HMPA / tetrahydrofuran; hexane / 0.33 h / -78 °C
3.2: tetrahydrofuran / -78 - 20 °C
4.1: 87 percent / xylene / 18 h / 180 °C
With
N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; di-isopropyl azodicarboxylate; bromine; magnesium; diisopropylamine; triphenylphosphine; mercury dichloride;
In
tetrahydrofuran; diethyl ether; hexane; xylene;
2.1: Mitsunobu inversion reaction / 4.1: Claisen-Ireland rearrangement reaction;
DOI:10.1055/s-2007-967937