2-NAPHTHALENEMETHYLAMINE HYDROCHLORIDE

Base Information

• Chemical Name: 2-NAPHTHALENEMETHYLAMINE HYDROCHLORIDE
• CAS No.: 2241-98-7
• Molecular Formula: C11H12ClN
• Molecular Weight: 193.676
• Hs Code.: 2921499090
• Mol file: 2241-98-7.mol

Synonyms:Naphthalen-2-yl-methylamine hydrochloride;

Chemical Property of 2-NAPHTHALENEMETHYLAMINE HYDROCHLORIDE

Chemical Property:

• Vapor Pressure: 9.96E-05mmHg at 25°C
• Melting Point: 268-270 °C
• Boiling Point: 333.2 °C at 760 mmHg
• Flash Point: 155.3 °C
• PSA: 26.02000
• LogP: 3.80080
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

Naphthalen-2-ylmethanamineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-NAPHTHALENEMETHYLAMINE HYDROCHLORIDE

There total 10 articles about 2-NAPHTHALENEMETHYLAMINE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2-naphthalenecarbonitrile (613-46-7) → naphthalen-2-ylmethanamine monohydrochloride (2241-98-7)

Guidance literature:

With hydrogenchloride; palladium 10% on activated carbon; hydrogen; In ethanol; water monomer; at 20 ℃; for 20h;

DOI:10.1080/07328303.2011.610544

Reference yield: 63.0%

2-naphthamide (2243-82-5) → naphthalen-2-ylmethanamine monohydrochloride (2241-98-7)

Guidance literature:

2-naphthamide; With bis(cyclopentadienyl)dihydrozirconium; 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane; at 20 ℃; for 24h; under 760.051 Torr; Inert atmosphere;

With hydrogenchloride; In diethyl ether; Inert atmosphere;

Reference yield:

2-naphthamide (2243-82-5) → 2-naphthalenecarbonitrile (613-46-7) + naphthalen-2-ylmethanamine monohydrochloride (2241-98-7)

Guidance literature:

2-naphthamide; With phenylsilane; C₃₆H₄₈F₆N₆NiO₅S₂; In toluene; at 110 ℃; for 12h; Inert atmosphere; Schlenk technique;

With hydrogenchloride; In diethyl ether; Overall yield = 90 percent; Overall yield = 100 percentChromat.;

DOI:10.1039/d1cc03537a

upstream raw materials:

2-naphthalenecarbonitrile

naphthalen-2-ylmethylamine

2-naphthamide

2-naphthaloyl chloride

Downstream raw materials:

(1R)-1-C-allyl-2,3,4-tri-O-benzyl-1-naphth-2-ylmethylamino-1-deoxy-D-xylitol

Refernces

• 1、 Yi, Jaeeun,Kim, Hyun Tae,Jaladi, Ashok Kumar,An, Duk Keun. "Deoxygenative hydroboration of primary, secondary, and tertiary amides: Catalyst-free synthesis of various substituted amines". . p. 129 - 132. Retrieved 2021/11/17.
• 2、 Guo, Chenjun,Zhang, Fangcao,Yu, Chong,Luo, Yunjie. "Reduction of Amides to Amines with Pinacolborane Catalyzed by Heterogeneous Lanthanum Catalyst La(CH2C6H4NMe2- o)3@SBA-15". . p. 13122 - 13135. Retrieved 2021/08/31.