magnesium;2H-naphthalen-2-ide;bromide

Base Information

• Chemical Name: magnesium;2H-naphthalen-2-ide;bromide
• CAS No.: 21473-01-8
• Molecular Formula: C10H7BrMg
• Molecular Weight: 231.375
• Hs Code.: 29319090
• European Community (EC) Number: 620-667-7
• DSSTox Substance ID: DTXSID50458375
• Mol file: 21473-01-8.mol

Synonyms:21473-01-8;magnesium;2H-naphthalen-2-ide;bromide;DTXSID50458375;YLVLCBHNULZXLQ-UHFFFAOYSA-M;WAA47301;J-014089

Chemical Property of magnesium;2H-naphthalen-2-ide;bromide

Chemical Property:

• Vapor Pressure: 0.159mmHg at 25°C
• Boiling Point: 65 °C
• Flash Point: 1 °F
• PSA: 0.00000
• Density: 0.951 g/mL at 25 °C
• LogP: 3.48560
• Storage Temp.: 2-8°C
• Sensitive.: Air & Moisture Sensitive
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 229.95815
• Heavy Atom Count: 12
• Complexity: 165

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Naphthylmagnesium bromide solution 0.5 M in THF ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F,C,F+
• Hazard Codes: F,C,F+,Xn
• Statements: 11-14-19-34-12-40-36/37
• Safety Statements: 16-26-36/37/39-45-36/37

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C=[C-]C=CC2=C1.[Mg+2].[Br-]

Technology Process of magnesium;2H-naphthalen-2-ide;bromide

There total 2 articles about magnesium;2H-naphthalen-2-ide;bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-bromonaphthalene (580-13-2) → 2-naphthalenylmagnesium bromide (21473-01-8)

Guidance literature:

With magnesium; ethylene dibromide; In tetrahydrofuran; 1) reflux, 2) r.t.;

DOI:10.1021/jo00028a043

Reference yield:

2-bromonaphthalene (580-13-2) + magnesium (7439-95-4) → 2-naphthalenylmagnesium bromide (21473-01-8)

Guidance literature:

In tetrahydrofuran; for 2h; Heating / reflux;

Reference yield: 99.0%

2-Methoxynaphthalene (93-04-9) + 2-naphthalenylmagnesium bromide (21473-01-8) → 2,2'-binaphthalene (612-78-2)

Guidance literature:

With bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; C₂₃H₂₈N₄; In tetrahydrofuran; m-xylene; at 60 ℃; for 4h; Inert atmosphere; Sealed tube;

DOI:10.1002/ejic.201900692

upstream raw materials:

2-bromonaphthalene

magnesium

Downstream raw materials:

3-(2-naphthyl)propan-1-ol

1-methyl-4-[2]naphthyl-piperidin-4-ol

(E)-3-(2-naphthyl)-2-propenal

4-(2-naphthyl)-4-oxobutyric acid

Refernces

• 1、 Escudero-Casao, Margarita,Licini, Giulia,Orlandi, Manuel. "Enantioselective α-Arylation of Ketones via a Novel Cu(I)-Bis(phosphine) Dioxide Catalytic System". supporting information. p. 3289 - 3294. Retrieved 2021/04/07.
• 2、 Yang, Wanfei,Chen, Huoji,Li, Jianxiao,Li, Chunsheng,Wu, Wanqing,Jiang, Huanfeng. "Palladium-catalyzed aerobic oxidative double allylic C-H oxygenation of alkenes: A novel and straightforward route to α,β-unsaturated esters". supporting information. p. 9575 - 9578. Retrieved 2015/06/08.