Technology Process of 2-(2-ortho-(2-hydroxyethyl)phenylpropyl)tetrahydropyrane ether
There total 3 articles about 2-(2-ortho-(2-hydroxyethyl)phenylpropyl)tetrahydropyrane ether which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
trimethylbenzylammonium hydroxide;
In
methanol; dimethyl sulfoxide;
at 60 - 65 ℃;
Product distribution / selectivity;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: tetrahydrofuran / -5 - 20 °C / Inert atmosphere
2: triphenylphosphine hydrobromide / dichloromethane / 48 h / 0 °C / Reflux
3: trimethylbenzylammonium hydroxide / dimethyl sulfoxide; methanol / 60 - 65 °C
With
trimethylbenzylammonium hydroxide; triphenylphosphine hydrobromide;
In
tetrahydrofuran; methanol; dichloromethane; dimethyl sulfoxide;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: triphenylphosphine hydrobromide / dichloromethane / 48 h / 0 °C / Reflux
2: trimethylbenzylammonium hydroxide / dimethyl sulfoxide; methanol / 60 - 65 °C
With
trimethylbenzylammonium hydroxide; triphenylphosphine hydrobromide;
In
methanol; dichloromethane; dimethyl sulfoxide;
