2-(2-{N-[2-(2-hydroxyethoxy)ethyl]phenylamino}ethoxy)ethanol

Base Information

• Chemical Name: 2-(2-{N-[2-(2-hydroxyethoxy)ethyl]phenylamino}ethoxy)ethanol
• CAS No.: 86336-41-6
• Molecular Formula: C₁₄H₂₃NO₄
• Molecular Weight: 269.341
• Mol file: 86336-41-6.mol

Synonyms:2-(2-{N-[2-(2-hydroxyethoxy)ethyl]phenylamino}ethoxy)ethanol

Chemical Property of 2-(2-{N-[2-(2-hydroxyethoxy)ethyl]phenylamino}ethoxy)ethanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(2-{N-[2-(2-hydroxyethoxy)ethyl]phenylamino}ethoxy)ethanol

There total 2 articles about 2-(2-{N-[2-(2-hydroxyethoxy)ethyl]phenylamino}ethoxy)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

2-methoxyethyl methanesulfonate (16427-44-4) + 2,2'-(phenylimino)bis[ethanol] (120-07-0) → 2-(2-{N-[2-(2-hydroxyethoxy)ethyl]phenylamino}ethoxy)ethanol (86336-41-6)

Guidance literature:

With sodium hydride; In acetonitrile; for 24h; Inert atmosphere; Reflux;

DOI:10.3390/molecules23020375

Reference yield:

2-(2-Chloroethoxy)ethanol (628-89-7) + aniline (62-53-3) → 2-(2-{N-[2-(2-hydroxyethoxy)ethyl]phenylamino}ethoxy)ethanol (86336-41-6)

Guidance literature:

With calcium carbonate; In water; for 12h; Heating;

DOI:10.1246/bcsj.68.2831

Reference yield: 39.0%

formic acid (64-18-6) + 2-(2-{N-[2-(2-hydroxyethoxy)ethyl]phenylamino}ethoxy)ethanol (86336-41-6) → 4-{bis-[2-(2-hydroxyethoxy)ethyl]amino}benzaldehyde (864962-40-3)

Guidance literature:

2-(2-{N-[2-(2-hydroxyethoxy)ethyl]phenylamino}ethoxy)ethanol; With hexamethylenetetramine; In ethanol; for 1h; Heating;

formic acid; With acetic acid; In ethanol; for 3h; Heating;

With hydrogenchloride; In ethanol; for 0.5h;

DOI:10.1039/b504408a

upstream raw materials:

2-(2-Chloroethoxy)ethanol

aniline

2-methoxyethyl methanesulfonate

2,2'-(phenylimino)bis[ethanol]

Downstream raw materials:

4-{bis-[2-(2-hydroxyethoxy)ethyl]amino}benzaldehyde

C₂₉H₃₅NO₉S₂

(C₆H₃CH₂)4(OCH₂CH₂OCH₂CH₂N(C₆H₄CHO)CH₂CH₂OCH₂CH₂O)2

Refernces

• 1、 Sakamoto, Hidefumi,Ishikawa, Junichi,Otomo, Makoto. "Silver Ion Selective Extraction with Dithiaza-, Tetrathiaza-, and Tetrathiadiazacrown Ether Derivatives". . p. 2831 - 2836. Retrieved 2007/10/03.