4-Methylmethamphetamine, (S)-

Base Information

• Chemical Name: 4-Methylmethamphetamine, (S)-
• CAS No.: 113358-79-5
• Molecular Formula: C₁₁H₁₇N
• Molecular Weight: 163.263
• UNII: 9HY63R6V4T
• Mol file: 113358-79-5.mol

Synonyms:4-Methylmethamphetamine, (S)-;9HY63R6V4T;UNII-9HY63R6V4T;113358-79-5;Benzeneethanamine, N,alpha,4-trimethyl-, (S)-;BENZENEETHANAMINE, N,.ALPHA.,4-TRIMETHYL-, (S)-

Chemical Property of 4-Methylmethamphetamine, (S)-

Chemical Property:

• XLogP3: 2.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 163.136099547
• Heavy Atom Count: 12
• Complexity: 114

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)CC(C)NC
• Isomeric SMILES: CC1=CC=C(C=C1)C[C@H](C)NC

Technology Process of 4-Methylmethamphetamine, (S)-

There total 4 articles about 4-Methylmethamphetamine, (S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

p-Tolylaceton (2096-86-8) + methylamine (74-89-5) → 4-methyl methamphetamine (113358-79-5)

Guidance literature:

With methanol; nickel; at 90 ℃; Hydrogenation;

Reference yield:

(4-methylphenyl)acetonitrile (2947-61-7) → 4-methyl methamphetamine (113358-79-5)

Guidance literature:

Multi-step reaction with 3 steps

1: ethyl acetate; ethanolic sodium ethylate

2: aqueous sulfuric acid / 80 - 100 °C

3: methanol; Raney nickel / 90 °C / Hydrogenation

With methanol; sulfuric acid; sodium ethanolate; nickel; ethyl acetate;

Reference yield:

1-(p-methylphenyl)-1-cyanoacetone (27243-91-0) → 4-methyl methamphetamine (113358-79-5)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous sulfuric acid / 80 - 100 °C

2: methanol; Raney nickel / 90 °C / Hydrogenation

With methanol; sulfuric acid; nickel;

upstream raw materials:

N-Methylformamide

p-Tolylaceton

methylamine

(4-methylphenyl)acetonitrile