trans-1-(but-2-en-1-yl)-4-chlorobenzene

Base Information

• Chemical Name: trans-1-(but-2-en-1-yl)-4-chlorobenzene
• CAS No.: 1074764-88-7
• Molecular Formula: C₁₀H₁₁Cl
• Molecular Weight: 166.65
• Mol file: 1074764-88-7.mol

Synonyms:trans-1-(but-2-en-1-yl)-4-chlorobenzene

Chemical Property of trans-1-(but-2-en-1-yl)-4-chlorobenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trans-1-(but-2-en-1-yl)-4-chlorobenzene

There total 5 articles about trans-1-(but-2-en-1-yl)-4-chlorobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-n-chlorophenylacetylene (873-73-4) + triethylamine (121-44-8) → trans-1-(but-2-en-1-yl)-4-chlorobenzene (1074764-88-7) + 1-(but-2-en-1-yl)-4-chlorobenzene

Guidance literature:

With C₃₇H₄₄CuN₂OP₂⁽¹⁺⁾*F₆P^(1-); In water; acetonitrile; for 18h; Overall yield = 50 percent; Schlenk technique; Inert atmosphere; Microwave irradiation;

Reference yield:

4-(p-chlorophenyl)-1-butene (3047-24-3) → trans-1-(but-2-en-1-yl)-4-chlorobenzene (1074764-88-7) + 1-(but-2-en-1-yl)-4-chlorobenzene

Guidance literature:

With diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; potassium carbonate; cobalt(II) aceylacetonate; bis[2-(diphenylphosphino)phenyl] ether; In N,N-dimethyl-formamide; at 25 ℃; for 16h; Overall yield = 86 %; Overall yield = 28.6 mg; stereoselective reaction; Irradiation;

DOI:10.1002/anie.201900849

Reference yield:

4-(p-chlorophenyl)-1-butene (3047-24-3) → trans-1-(but-2-en-1-yl)-4-chlorobenzene (1074764-88-7)

Guidance literature:

With 2,6-di-tert-butyl-pyridine; C₂₆H₄₆IrNO₇P⁽¹⁺⁾*C₃₂H₁₂BF₂₄^(1-); In 1,2-dichloro-ethane; at 50 ℃; for 48h; Time; regioselective reaction; Inert atmosphere;

DOI:10.1021/jacs.0c11601

upstream raw materials:

buta-1,3-diene

chlorobenzene

4-(p-chlorophenyl)-1-butene

4-chlorobenzyl bromide

Refernces

• 1、 Zheng, Limeng,Jiang, Qinfang,Bao, Hanyang,Zhou, Bingwei,Luo, Shu-Ping,Jin, Hongwei,Wu, Huayue,Liu, Yunkui. "Tertiary amines acting as Alkyl radical equivalents enabled by a P/N heteroleptic Cu(I) photosensitizer". supporting information. p. 8888 - 8893. Retrieved 2020/11/30.
• 2、 -. "Synthetic method of 1,2-disubstituted olefin compounds". Paragraph 0044-0047. . Retrieved 2019/12/25.