octyl-D-Val-D-Dab-Gly-D-Ala-D-Trp-Ser-Dab-D-Dab-Phe-Glu-Val-D-allo-Ile-Ala-OH

Base Information

• Chemical Name: octyl-D-Val-D-Dab-Gly-D-Ala-D-Trp-Ser-Dab-D-Dab-Phe-Glu-Val-D-allo-Ile-Ala-OH
• CAS No.: 1628113-75-6
• Molecular Formula: C₇₂H₁₁₃N₁₇O₁₈
• Molecular Weight: 1504.79
• Mol file: 1628113-75-6.mol

Synonyms:octyl-D-Val-D-Dab-Gly-D-Ala-D-Trp-Ser-Dab-D-Dab-Phe-Glu-Val-D-allo-Ile-Ala-OH

Chemical Property of octyl-D-Val-D-Dab-Gly-D-Ala-D-Trp-Ser-Dab-D-Dab-Phe-Glu-Val-D-allo-Ile-Ala-OH

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of octyl-D-Val-D-Dab-Gly-D-Ala-D-Trp-Ser-Dab-D-Dab-Phe-Glu-Val-D-allo-Ile-Ala-OH

There total 1 articles about octyl-D-Val-D-Dab-Gly-D-Ala-D-Trp-Ser-Dab-D-Dab-Phe-Glu-Val-D-allo-Ile-Ala-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Fmoc-Ala-O-Wang resin + Octanoic acid (124-07-2) + N-(fluoren-9-ylmethoxycarbonyl)glycine (29022-11-5) + Fmoc-Val-OH (68858-20-8) + N-Fmoc L-Phe (35661-40-6) + N-(9-Fluorenylmethoxycarbonyl)-D-alloisoleucine (118904-37-3,251316-98-0) + Fmoc-Glu(OtBu)-OH (71989-18-9) + N-(9-fluorenylmethoxycarbonyl)-D-alanine (35661-38-2,35661-39-3,79990-15-1,136132-75-7) + N-(9H-fluoren-9-ylmethoxycarbonyl)-L-serine (73724-45-5) + (S)-4-tert-butoxycarbonylamino-2-(9H-fluoren-9-ylmethoxycarbonylamino)butyric acid (125238-99-5,114360-56-4) + N-(9-fluorenylmethoxycarbonyl)-D-valine (84624-17-9) + N-α-(9-fluorenylmethyloxycarbonyl)-N-γ-tert-butyloxycarbonyl-D-2,4-diaminobutyric acid (114360-56-4) → octyl-D-Val-D-Dab-Gly-D-Ala-D-Trp-Ser-Dab-D-Dab-Phe-Glu-Val-D-allo-Ile-Ala-OH (1628113-75-6)

Guidance literature:

Fmoc-Ala-O-Wang resin; With piperidine; In N,N-dimethyl-formamide; for 0.2h; Wang resin

N-(9-Fluorenylmethoxycarbonyl)-D-alloisoleucine; With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In N,N-dimethyl-formamide; for 1h; Wang resin

Octanoic acid; N-(fluoren-9-ylmethoxycarbonyl)glycine; Fmoc-Val-OH; N-Fmoc L-Phe; Fmoc-Glu(OtBu)-OH; N-(9-fluorenylmethoxycarbonyl)-D-alanine; N-(9H-fluoren-9-ylmethoxycarbonyl)-L-serine; (S)-4-tert-butoxycarbonylamino-2-(9H-fluoren-9-ylmethoxycarbonylamino)butyric acid; N-(9-fluorenylmethoxycarbonyl)-D-valine; N-α-(9-fluorenylmethyloxycarbonyl)-N-γ-tert-butyloxycarbonyl-D-2,4-diaminobutyric acid; Protected D-Trp derivative;

DOI:10.1002/cbic.201402024

upstream raw materials:

Octanoic acid

N-(fluoren-9-ylmethoxycarbonyl)glycine

Fmoc-Val-OH

N-Fmoc L-Phe

Refernces