Technology Process of 2-Iodosyl-4-pentyl-benzoic acid
There total 4 articles about 2-Iodosyl-4-pentyl-benzoic acid which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
dihydrogen peroxide; acetic anhydride;
at 40 ℃;
for 20h;
DOI:10.1021/jo00305a011
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 2 M NaOH, NaBH4 / H2O; methanol / 0.58 h / Ambient temperature
2: 1) n-BuLi, tetramethylethylenediamine, 2) I2 / 1) petroleum ether, hexane, a) reflux, 11 h, b) room temp., 13 h, 2) -78 deg C to room temp., 1 h
3: 63 percent / KMnO4 / tetramethylphosphonium chloride / H2O; benzene / 3 h / Ambient temperature
4: 90 percent / acetic anhydride, 30percent H2O2 / 20 h / 40 °C
With
sodium hydroxide; sodium tetrahydroborate; potassium permanganate; n-butyllithium; N,N,N,N,-tetramethylethylenediamine; dihydrogen peroxide; iodine; acetic anhydride;
tetramethylphosphonium chloride;
In
methanol; water; benzene;
DOI:10.1021/jo00305a011
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1) n-BuLi, tetramethylethylenediamine, 2) I2 / 1) petroleum ether, hexane, a) reflux, 11 h, b) room temp., 13 h, 2) -78 deg C to room temp., 1 h
2: 63 percent / KMnO4 / tetramethylphosphonium chloride / H2O; benzene / 3 h / Ambient temperature
3: 90 percent / acetic anhydride, 30percent H2O2 / 20 h / 40 °C
With
potassium permanganate; n-butyllithium; N,N,N,N,-tetramethylethylenediamine; dihydrogen peroxide; iodine; acetic anhydride;
tetramethylphosphonium chloride;
In
water; benzene;
DOI:10.1021/jo00305a011