5,4'-diacetoxyflavone-7-O-D-triacetoxyglucuronic acid methyl ester

Base Information

• Chemical Name: 5,4'-diacetoxyflavone-7-O-D-triacetoxyglucuronic acid methyl ester
• CAS No.: 34340-20-0
• Molecular Formula: C₃₂H₃₀O₁₆
• Molecular Weight: 670.581
• Mol file: 34340-20-0.mol

Synonyms:5,4'-diacetoxyflavone-7-O-D-triacetoxyglucuronic acid methyl ester

Chemical Property of 5,4'-diacetoxyflavone-7-O-D-triacetoxyglucuronic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5,4'-diacetoxyflavone-7-O-D-triacetoxyglucuronic acid methyl ester

There total 3 articles about 5,4'-diacetoxyflavone-7-O-D-triacetoxyglucuronic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

methyl α-bromotriacetoxyglucuronic acid + apigenin triacetate (3316-46-9) → 5,4'-diacetoxyflavone-7-O-D-triacetoxyglucuronic acid methyl ester (34340-20-0)

Guidance literature:

apigenin triacetate; With potassium carbonate; In acetone; at 30 - 50 ℃;

With tetrabutylammomium bromide; In acetone; for 0.166667h;

methyl α-bromotriacetoxyglucuronic acid; In acetone; Reagent/catalyst; Temperature;

Reference yield:

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one (520-36-5) → 5,4'-diacetoxyflavone-7-O-D-triacetoxyglucuronic acid methyl ester (34340-20-0)

Guidance literature:

Multi-step reaction with 2 steps

1.1: pyridine / 8 h / 140 °C

2.1: potassium carbonate / acetone / 30 - 50 °C

2.2: 0.17 h

With pyridine; potassium carbonate; In acetone;

Reference yield:

→ 5,4'-diacetoxyflavone-7-O-D-triacetoxyglucuronic acid methyl ester (34340-20-0)

Guidance literature:

Verb.1: 1) H2-Pd/C 2) Acetylierung;

upstream raw materials:

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

apigenin triacetate

Downstream raw materials:

apigenin 7-O-β-D-glucopyranosiduronic acid methyl ester

apigenin-7-O-β-D-glucuronide

Refernces