N-(5-(5-chloropentyl)-1,3,4-thiadiazol-2-yl)-4-dodecyl benzenesulfonamide

Base Information

• Chemical Name: N-(5-(5-chloropentyl)-1,3,4-thiadiazol-2-yl)-4-dodecyl benzenesulfonamide
• CAS No.: 1271729-65-7
• Molecular Formula: C₂₅H₄₀ClN₃O₂S₂
• Molecular Weight: 514.197
• Mol file: 1271729-65-7.mol

Synonyms:N-(5-(5-chloropentyl)-1,3,4-thiadiazol-2-yl)-4-dodecyl benzenesulfonamide

Chemical Property of N-(5-(5-chloropentyl)-1,3,4-thiadiazol-2-yl)-4-dodecyl benzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(5-(5-chloropentyl)-1,3,4-thiadiazol-2-yl)-4-dodecyl benzenesulfonamide

There total 4 articles about N-(5-(5-chloropentyl)-1,3,4-thiadiazol-2-yl)-4-dodecyl benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Amino-5-(5-bromopentyl)-1,3,4-thiadiazole + p-dodecylbenzenesulfonyl chloride (52499-14-6) → N-(5-(5-chloropentyl)-1,3,4-thiadiazol-2-yl)-4-dodecyl benzenesulfonamide (1271729-65-7) + N-(5-(5-bromopentyl)-1,3,4-thiadiazol-2-yl)-4-dodecylbenzenesulfonamide (1178893-79-2)

Guidance literature:

With pyridine; at 20 ℃; for 5h;

Reference yield:

6-bromohexanoic acid (4224-70-8) → N-(5-(5-chloropentyl)-1,3,4-thiadiazol-2-yl)-4-dodecyl benzenesulfonamide (1271729-65-7)

Guidance literature:

Multi-step reaction with 2 steps

1: sulfuric acid / 12 h / 80 - 90 °C

2: pyridine / 5 h / 20 °C

With pyridine; sulfuric acid;

Reference yield:

1-dodecylbenzene (123-01-3) → N-(5-(5-chloropentyl)-1,3,4-thiadiazol-2-yl)-4-dodecyl benzenesulfonamide (1271729-65-7)

Guidance literature:

Multi-step reaction with 3 steps

1: sulfuric acid / 1 h / 90 °C

2: trichlorophosphate / 20 - 170 °C

3: pyridine / 5 h / 20 °C

With pyridine; sulfuric acid; trichlorophosphate;

upstream raw materials:

p-dodecylbenzenesulfonyl chloride

6-bromohexanoic acid

1-dodecylbenzene

potassium 4-dodecylbenzenesulfonate

Refernces