6,7-dihydroxy-3-methylcinnoline

Base Information

• Chemical Name: 6,7-dihydroxy-3-methylcinnoline
• CAS No.: 1176784-51-2
• Molecular Formula: C₉H₈N₂O₂
• Molecular Weight: 176.175
• Mol file: 1176784-51-2.mol

Synonyms:6,7-dihydroxy-3-methylcinnoline

Chemical Property of 6,7-dihydroxy-3-methylcinnoline

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6,7-dihydroxy-3-methylcinnoline

There total 2 articles about 6,7-dihydroxy-3-methylcinnoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

S(-)-carbidopa (302-53-4,14585-65-0,28860-95-9,28875-92-5,31823-41-3) → 1-(3,4-dihydroxyphenyl)-2-propanone (2503-44-8) + 6,7-dihydroxy-3-methylcinnoline (1176784-51-2) + 3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid (53832-94-3)

Guidance literature:

With bovine myeloperoxidase; dihydrogen peroxide; In aq. buffer; at 20 ℃; pH=6; Reagent/catalyst; Catalytic behavior; Enzymatic reaction;

DOI:10.1016/j.bbagen.2018.04.007

Reference yield:

S(-)-carbidopa (302-53-4,14585-65-0,28860-95-9,28875-92-5,31823-41-3) → 6,7-dihydroxy-3-methylcinnoline (1176784-51-2) + 3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid (53832-94-3)

Guidance literature:

With mushroom tyrosinase, specifi activity 2956 U/mg; oxygen; In tetralin; for 0.5h; pH=6.8; aq. phosphate buffer;

DOI:10.1016/j.bmcl.2009.05.002

upstream raw materials:

S(-)-carbidopa

Refernces

• 1、 G?sowska-Bajger, Beata,Nishigaya, Yuki,Hirsz-Wiktorzak, Krystyna,Rybczyńska, Anna,Yamazaki, Toshimasa,Wojtasek, Hubert. "Interference of carbidopa and other catechols with reactions catalyzed by peroxidases". . p. 1626 - 1634. Retrieved 2018.