Technology Process of 3-Pyridinol,4,6-dimethyl-,1-oxide(9CI)
There total 6 articles about 3-Pyridinol,4,6-dimethyl-,1-oxide(9CI) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
3-chloro-benzenecarboperoxoic acid;
In
dichloromethane;
at 20 ℃;
for 16h;
DOI:10.1039/c6ob00244g
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 98 percent / H2 / 5percent Pd/C / ethanol / 2 h / 3102.9 Torr
2: 51 percent / 10percent aq. sulfuric acid, aq. sodium nitrite / a.) 0 deg C, 15 min, b.) reflux, 15 min
3: 37 percent / 30percent aq. hydrogen peroxide, glacial acetic acid / 9 h / 80 °C
With
sulfuric acid; hydrogen; dihydrogen peroxide; acetic acid; sodium nitrite;
palladium on activated charcoal;
In
ethanol;
DOI:10.1021/jm00098a011
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 18 percent / fuming sulfuric acid, potassium nitrate / 16 h / 100 - 120 °C
2: 98 percent / H2 / 5percent Pd/C / ethanol / 2 h / 3102.9 Torr
3: 51 percent / 10percent aq. sulfuric acid, aq. sodium nitrite / a.) 0 deg C, 15 min, b.) reflux, 15 min
4: 37 percent / 30percent aq. hydrogen peroxide, glacial acetic acid / 9 h / 80 °C
With
sulfuric acid; hydrogen; dihydrogen peroxide; acetic acid; potassium nitrate; sodium nitrite;
palladium on activated charcoal;
In
ethanol;
DOI:10.1021/jm00098a011