(S)-2-dimethylamino-1-phenyl-propan-1-one; O,O'-dibenzoyl-L_g-hydrogentartrate

Base Information

• Chemical Name: (S)-2-dimethylamino-1-phenyl-propan-1-one; O,O'-dibenzoyl-L_g-hydrogentartrate
• CAS No.: 35026-78-9
• Molecular Formula: C₁₁H₁₅NO*C₁₈H₁₄O₈
• Molecular Weight: 535.551
• Mol file: 35026-78-9.mol

Synonyms:(S)-2-dimethylamino-1-phenyl-propan-1-one; O,O'-dibenzoyl-L_g-hydrogentartrate

Chemical Property of (S)-2-dimethylamino-1-phenyl-propan-1-one; O,O'-dibenzoyl-L_g-hydrogentartrate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-2-dimethylamino-1-phenyl-propan-1-one; O,O'-dibenzoyl-L_g-hydrogentartrate

There total 3 articles about (S)-2-dimethylamino-1-phenyl-propan-1-one; O,O'-dibenzoyl-L_g-hydrogentartrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

O,O'-dibenzoyl-D-tartaric acid (17026-42-5) + metamfepramone (15351-09-4) → (S)-2-dimethylamino-1-phenyl-propan-1-one; O,O'-dibenzoyl-Lg-hydrogentartrate (35026-78-9)

Guidance literature:

With sodium hydroxide; In water; acetone; at 20 ℃;

DOI:10.1039/c5ob01306b

Reference yield:

1-phenyl-propan-1-one (93-55-0) → (S)-2-dimethylamino-1-phenyl-propan-1-one; O,O'-dibenzoyl-Lg-hydrogentartrate (35026-78-9)

Guidance literature:

Multi-step reaction with 3 steps

1: acetic acid; bromine / 22 h / 20 °C

2: triethylamine / dichloromethane / 21 h / 20 °C

3: sodium hydroxide / acetone; water / 20 °C

With bromine; acetic acid; triethylamine; sodium hydroxide; In dichloromethane; water; acetone;

DOI:10.1039/c5ob01306b

Reference yield:

2-bromo-1-phenyl-1-propanone (2114-00-3) → (S)-2-dimethylamino-1-phenyl-propan-1-one; O,O'-dibenzoyl-Lg-hydrogentartrate (35026-78-9)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 21 h / 20 °C

2: sodium hydroxide / acetone; water / 20 °C

With triethylamine; sodium hydroxide; In dichloromethane; water; acetone;

DOI:10.1039/c5ob01306b

upstream raw materials:

O,O'-dibenzoyl-D-tartaric acid

metamfepramone

2-bromo-1-phenyl-1-propanone

1-phenyl-propan-1-one

Downstream raw materials:

(S)-2-(dimethylamino)propiophenone

Refernces