Technology Process of (R)-N-(2-(9H-fluoren-9-ylidene)ethyl)-1-(4-fluorophenyl)ethanamine
There total 4 articles about (R)-N-(2-(9H-fluoren-9-ylidene)ethyl)-1-(4-fluorophenyl)ethanamine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
hydrogenchloride;
In
diethyl ether; hexane;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: diisobutylaluminium hydride / hexane / Inert atmosphere; Cooling with acetone-dry ice
2.1: Dess-Martin periodane / dichloromethane / 1.5 h / 20 °C / Inert atmosphere; Sealed tube
3.1: phosphotungstic acid hydrate / 1,2-dichloro-ethane / 0.17 h / 20 °C
3.2: 20 °C
4.1: hydrogenchloride / diethyl ether; hexane
With
hydrogenchloride; phosphotungstic acid hydrate; diisobutylaluminium hydride; Dess-Martin periodane;
In
diethyl ether; hexane; dichloromethane; 1,2-dichloro-ethane;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: Dess-Martin periodane / dichloromethane / 1.5 h / 20 °C / Inert atmosphere; Sealed tube
2.1: phosphotungstic acid hydrate / 1,2-dichloro-ethane / 0.17 h / 20 °C
2.2: 20 °C
3.1: hydrogenchloride / diethyl ether; hexane
With
hydrogenchloride; phosphotungstic acid hydrate; Dess-Martin periodane;
In
diethyl ether; hexane; dichloromethane; 1,2-dichloro-ethane;