O-nitro-2-benzamidoethanol

Base Information

• Chemical Name: O-nitro-2-benzamidoethanol
• CAS No.: 38406-53-0
• Molecular Formula: C₉H₁₀N₂O₄
• Molecular Weight: 210.189
• Mol file: 38406-53-0.mol

Synonyms:O-nitro-2-benzamidoethanol

Chemical Property of O-nitro-2-benzamidoethanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of O-nitro-2-benzamidoethanol

There total 4 articles about O-nitro-2-benzamidoethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2-phenyl-1,3-oxazoline (7127-19-7) → O-nitro-2-benzamidoethanol (38406-53-0)

Guidance literature:

With tert.-butylnitrite; In 1,4-dioxane; at 80 ℃; for 2h; Time;

Reference yield: 57.0%

N-(2-hydroxyethyl)-benzamide (18838-10-3) → O-nitro-2-benzamidoethanol (38406-53-0)

Guidance literature:

With nitric acid; acetic anhydride; at 0 ℃; for 0.0833333h;

Reference yield:

benzoyl chloride (98-88-4) → O-nitro-2-benzamidoethanol (38406-53-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 63 percent / NaHCO₃ / ethyl acetate; H₂O / 4 h / Ambient temperature

2: 57 percent / HNO₃, acetic anhydride / 0.08 h / 0 °C

With nitric acid; acetic anhydride; sodium hydrogencarbonate; In water; ethyl acetate;

upstream raw materials:

N-(2-hydroxyethyl)-benzamide

benzoyl chloride

2-phenyl-1,3-oxazoline

benzonitrile

Downstream raw materials:

N-methylbenzamide

N-(2-hydroxyethyl)-benzamide

Refernces

• 1、 Easton, Christopher J.,Ivory, Andrew J.,Smith, Craig A.. "Nitrate esters in the generation of amino acid radicals". . p. 503 - 507. Retrieved 2007/10/03.