acetic acid 2-oxo-1,2,2-triphenylethyl ester

Base Information

• Chemical Name: acetic acid 2-oxo-1,2,2-triphenylethyl ester
• CAS No.: 4917-96-8
• Molecular Formula: C₂₂H₁₈O₃
• Molecular Weight: 330.383
• Mol file: 4917-96-8.mol

Synonyms:acetic acid 2-oxo-1,2,2-triphenylethyl ester

Chemical Property of acetic acid 2-oxo-1,2,2-triphenylethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of acetic acid 2-oxo-1,2,2-triphenylethyl ester

There total 10 articles about acetic acid 2-oxo-1,2,2-triphenylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

α-benzoyldiphenylmethyl chloride (2510-77-2) + acetic acid (64-19-7,77671-22-8) → acetic acid 2-oxo-1,2,2-triphenylethyl ester (4917-96-8)

Guidance literature:

With silver tetrafluoroborate; silver carbonate; In dichloromethane; at -60 - 0 ℃;

DOI:10.1016/S0040-4039(03)00513-6

Reference yield:

α-phenylbenzoin (4237-46-1) → acetic acid 2-oxo-1,2,2-triphenylethyl ester (4917-96-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 64 percent / pyridine; thionyl chloride / 0 °C

2: 89 percent / silver(I) carbonate; silver(I) tetrafluoroborate / CH₂Cl₂ / -60 - 0 °C

With pyridine; silver tetrafluoroborate; thionyl chloride; silver carbonate; In dichloromethane;

DOI:10.1016/j.tet.2006.11.015

Reference yield:

2-methoxy-2,3,3-triphenyl-oxirane (7714-70-7) → acetic acid 2-oxo-1,2,2-triphenylethyl ester (4917-96-8)

Guidance literature:

Multi-step reaction with 2 steps

1: methanol.HCl

2: acetic acid

With hydrogenchloride; acetic acid;

DOI:10.1021/ja01632a024

upstream raw materials:

2-methoxy-2,3,3-triphenyl-oxirane

acetic anhydride

methoxy-2 triphenyl-1,2,2 ethanone-1

α-phenylbenzoin

Refernces

• 1、 Ashraf, M. Arfan,Jones, Matthew A.,Kelly, Natalie E.,Mullaney, Alex,Snaith, John S.,Williams, Iwan. "Synthesis and photolysis studies of carboxylic esters of 2-hydroxy-1,2,2-triphenylethanone: A novel tandem photocyclisation". . p. 3151 - 3154. Retrieved 2007/10/03.