2-Hydroxy-1,2,2-triphenylethanone

Base Information

• Chemical Name: 2-Hydroxy-1,2,2-triphenylethanone
• CAS No.: 4237-46-1
• Molecular Formula: C20H16 O2
• Molecular Weight: 288.346
• Mol file: 4237-46-1.mol

Synonyms:Acetophenone,2-hydroxy-2,2-diphenyl- (6CI,7CI,8CI); 2,2-Diphenyl-2-hydroxyacetophenone;2-Hydroxy-1,2,2-triphenylethanone; 2-Phenylbenzoin; Benzilophenone; NSC 4641; a-Phenylbenzoin

Chemical Property of 2-Hydroxy-1,2,2-triphenylethanone

Chemical Property:

• Vapor Pressure: 1.78E-09mmHg at 25°C
• Boiling Point: 465.8°C at 760 mmHg
• Flash Point: 198.1°C
• PSA: 37.30000
• Density: 1.186g/cm³
• LogP: 3.80540

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Hydroxy-1,2,2-triphenylethanone

There total 50 articles about 2-Hydroxy-1,2,2-triphenylethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1,2,2-triphenylethan-1-one (1733-63-7) → benzophenone (119-61-9) + α-phenylbenzoin (4237-46-1)

Guidance literature:

With air; water; 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile; at 50 ℃; for 21h;

DOI:10.1055/s-0028-1087674

Reference yield: 78.0%

(2,3-Dimethyl-benzo[g]indol-1-yl)-oxo-acetic acid ethyl ester (114570-16-0) + phenylmagnesium bromide → phenylglyoxylic acid ethyl ester (1603-79-8) + 2,3-dimethylbenz<6,7>indole (36729-21-2) + α-phenylbenzoin (4237-46-1) + benzil (134-81-6) + ethyl benzilate (52182-15-7)

Guidance literature:

In acetone; Product distribution;

DOI:10.1007/BF00475361

Reference yield: 78.0%

benzophenone (119-61-9) + benzonitrile (100-47-0) → α-phenylbenzoin (4237-46-1)

Guidance literature:

With samarium diiodide; In tetrahydrofuran; for 4h; Heating;

DOI:10.1016/S0040-4039(98)01984-4

upstream raw materials:

diethyl ether

methyl cyanoformate

1,2,2-triphenylethan-1-one

2-bromo-1,2,2-triphenyl-ethanone

Downstream raw materials:

1,1,1-triphenylacetone

1,1,2-triphenylpropane-1,2-diol

benzoic acid 2-oxo-1,2,2-triphenylethyl ester

acetic acid 2-oxo-1,2,2-triphenylethyl ester

Refernces

• 1、 Abe, Toyohiko,Kawai, Akio,Kajii, Yoshizumi,Shibuya, Kazuhiko,Obi, Kinichi. "Solvent effects on the complex formation of benzophenone ketyl radical and triethylamine". . p. 1457 - 1462. Retrieved 1999.
• 2、 Ma, Zhiming,Ren, Peng,Song, Tao,Xiao, Jianliang,Yang, Yong,Yuan, Youzhu. "A Bifunctional Iron Nanocomposite Catalyst for Efficient Oxidation of Alkenes to Ketones and 1,2-Diketones". . p. 4617 - 4629. Retrieved 2020/05/19.
• 3、 Jang, Sukjin,Chowdhury, Azhad,Kang, Jeonghee,Lee, Jong I.. "Photorelease study of γ-amino glutamate from 1,2,2-triphenyl-ethanone". . p. 230 - 235. Retrieved 2014/05/20.